Search for dissertations about: "hypoglossal nerve"

Showing result 1 - 5 of 6 swedish dissertations containing the words hypoglossal nerve.

  1. 1. Clusterin and Megalin in The Spinal Cord

    Author : Grzegorz Wicher; Hakan Aldskogius; Lars Hillered; Anders Lewen; Robin Franklin; Uppsala universitet; []
    Keywords : Neurosciences; nerve degeneration; hypoglossal nerve; chaperone; apolipoprotein; development; transcription factor; astrocyte; glial differentiation; myelin; cell signalling; Neurovetenskap;

    Abstract : Nerve injury induces up-regulation of the chaperone protein clusterin in affected neurons and adjacent astrocytes but the functional significance of this response is unclear. We find that motor neuron survival is significantly greater in clusterin(+/+) compared to (-/-) mice. READ MORE

  2. 2. Role of corticotropin-releasing factor, somatostatin and leptin in vagal nerve function and control of gastric emptying

    Author : Ulrika Smedh; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The overall aim of this thesis was to study the effects of centrally acting CRF and leptin, and peripherally acting somatostatin on gastric emptying of glucose. Freely moving rats bearing chronic intragastric fistulas received intragastric infusions (1.0 ml/min) of glucose (12.5 % or 25 %) during 6-18 min. READ MORE

  3. 3. Adult neural stem cells and their differentiation choices : examples from experimental inflammation and transplantation

    Author : Cynthia Pérez Estrada; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The aim of this thesis is to study how inflammation influences the fate of NPCs, which can impact the regenerative capacities of the CNS. In paper I, we used a hypoglossal nerve avulsion model, to study if survival, differentiation, and integration of transplanted NPCs could be achieved. READ MORE

  4. 4. On the cholinergic c-bouton

    Author : Johan Hellström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Acetylcholine; Brainstem; Immunohistochemistry; In situ hybridization; Motoneurons; Muscarinic receptors; Rat; Spinal cord; Ventral horn cells;

    Abstract : The cholinergic C-bouton is a large nerve terminal type exclusively contacting motoneuron cell somata and proximal dendrites. C-boutons are characterized by subsurface cisterns found beneath the postsynaptic membrane, which is an exclusive feature for these nerve terminals. The origin of the C-boutons is unknown. READ MORE

  5. 5. Clinical translation of a regeneration strategy for spinal cord injury

    Author : Arvid Frostell; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The complex and vulnerable tissue of the spinal cord does not heal after injury, leaving patients with lifelong disability after spinal cord injury (SCI). Many milestones have been reached during the last century through specialized centers for SCI, greatly increasing life expectancy and quality of life by battling common medical problems such as urinary tract infections, pressure ulcers, spasticity, neurogenic pain, and sexual function as well as providing means of rehabilitation to a meaningful and productive life after SCI. READ MORE