Search for dissertations about: "hypophysectomy"

Showing result 1 - 5 of 8 swedish dissertations containing the word hypophysectomy.

  2. 1. GH/IGF-I axis regulation of cardiovascular and neuronal gene expression and function

    Author : Anna Barlind; Göteborgs universitet; []
    Keywords : Growth hormone; rat; hypophysectomy; vascular resistance; gene expression; place learning; Intellicage; hexarelin; CNS; hippocampus; neurogenesis; cell survival; mouse;

    Abstract : Abstract Cardiovascular disease is a major cause of mortality in the Western world. Another important clinical condition is brain damage due to radiation therapy in cancer patients. This has neurological impairments presenting in the survivors. For both these conditions, it is important to develop new therapeutic strategies. READ MORE

  4. 2. Connexin43 in astroglial gap junctions. Regulation by age, neurotransmitters, GH and IGF-I

    Author : N David Åberg; Göteborgs universitet; []
    Keywords : Connexin43; rat; development; hypophysectomy; primary culture; ; mRNA; gap junction; somatotropin; IGF-I; serotonin; glutamate; ; brain region heterogeneity; calcium wave; astrocyte; astroglial cell; ; gap junctional coupling.;

    Abstract : Connexins form gap junctions that are aqueous pores allowing low-molecular (.... READ MORE

  5. 3. The interplay between the endocrine and cardiovascular systems. A study of the hormonal influence on cardiovascular function and endothelial nitric oxide synthase (eNOS) expression

    Author : Anna Wickman; Göteborgs universitet; []
    Keywords : hypophysectomy · growth hormone · insulin-like growth factor-I · estrogen · vascular reactivity · endothelial function · endothelial nitric oxide synthase · nitric oxide · cardiovascular function · vasculature · kidney · hypertension;

    Abstract : During the present thesis, special interest was focused on the cardiovascular effects of growth hormone (GH) and estrogen (E2) and combined treatment of GH+E2, in particular the possible effects on endothelial nitric oxide synthase (eNOS) expression and nitric oxide (NO) bioavailability for maintaining cardiovascular homeostasis. The possible role of fluid mechanical force e. READ MORE

  6. 4. Hormonal regulation of hepatic cholesterol and lipoprotein metabolism : effects of estrogen and growth hormone

    Author : Paolo Parini; Karolinska Institutet; Karolinska Institutet; []
    Keywords : aging; atherosclerosis; bile acids; estrogen; estrogen receptor; cholesterol; growth hormone; growth hormone receptor; cholesterol 7[alpha]-hydroxylase; high density lipoprotein; hydroxy-methylglutaryl-coenzyme A reductase; hormones; hypercholesterolemia; hypophysectomy; insulin-like growth factor-I; low density lipoproteins;

    Abstract : Coronary heart disease is the result of the progression of atherosclerotic lesions, and represents the major cause of death in western countries. Age, male sex, plasma cholesterol, hypertension and smoking are major risk factors for atherosclerosis. READ MORE

  7. 5. Growth hormone regulation of LFABP and PPARa. Genes involved in hepatic lipid metabolism

    Author : Linda Carlsson; Göteborgs universitet; []
    Keywords : Growth hormone; fatty acids; rat; hepatocyte; LFABP; C EBPa; PPARa;

    Abstract : Growth hormone (GH) is known to have several important effects in the control of metabolism. The aim of these studies was to investigate how GH regulates genes involved in fatty acid transport and metabolism in the liver and the interaction between GH and fatty acids in this regulation. READ MORE