Search for dissertations about: "hypoxia ischemia"

Showing result 1 - 5 of 54 swedish dissertations containing the words hypoxia ischemia.

  1. 1. Exploring immune cell functions and ways to make use of them

    Author : Evelina Vågesjö; Mia Phillipson; Michael Hickey; Uppsala universitet; []
    Keywords : leukocytes; neutrophils; macrophages; regulatory T cells; chemokines; VEGF-A; hypoxia; ischemia; muscle; Islets of Langerhans; diabetes; transplantation; wound healing;

    Abstract : In addition to host defense, alternative functions of immune cells are emerging. Immune cells are crucial during healing of injured tissue, in formation of new blood vessels, angiogenesis, and also in maintaining the balance in inflammation having immune regulating functions. READ MORE

  2. 2. Apoptosis-related mechanisms in the immature brain after hypoxia-ischemia

    Author : Xiaoyang Wang; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : hypoxia-ischemia; neonatal; caspase; ERK; XIAP; EPO; asialoEPO; brain;

    Abstract : Aims: To characterize the activation of caspases-3 and extracellular signal-regulated kinase (ERK) in the neonatal brain after hypoxia-ischemia (HI) injury and evaluate the neuroprotective effect of X-linked inhibitor of apoptosis (XIAP) protein, erythropoietin (EPO) and the non-erythropoietic derivative asialoEPO. Methods: Seven-day-old rats or 9-day-old mice were subjected to HI. READ MORE

  3. 3. Electrical Bioimpedance Cerebral Monitoring: Fundamental Steps towards Clinical Application

    Author : Fernando Seoane Martinez; Fernando Seoane Martínez; Fernando Seoane; Chalmers University of Technology; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedical Instrumentation; Ischemia; Hypoxia; Non-invasive Monitoring; Electrical Bioimpedance Spectroscopy; Stroke; Impedance Measurements; Brain Monitoring; biomedicin; bioteknik; non-invasive monitoring; electrical bioimpedance; spectroscopy; biomedical instrumentation;

    Abstract : Neurologically related injuries cause a similar number of deaths as cancer, and brain damage is the second commonest cause of death in the world and probably the leading cause of permanent disability. The devastating effects of most cases of brain damage could be avoided if it were detected and medical treatment initiated in time. READ MORE

  4. 4. Aspects of pathological apoptosis in the immature brain after hypoxia-ischemia

    Author : Ulrika Hallin; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : neonatal; rat; brain; hypoxia-ischemia; necrosis; apoptosis; calpain; caspase; Bcl-2; Bax; mitochondria; calcineurin.;

    Abstract : The cause of mechanisms underlying perinatal brain injury is not fully known, but it results in a wide variety of neurological impairments in the affected children. When injured, neurons of the newborn brain are prone to undergo programmed cell death, apoptosis, since this genetic program is normally activated in some cells during development of the nervous system, even in the perinatal period. READ MORE

  5. 5. Inflammatory response in the immature brainafter hypoxia-ischemia. Application of microarray and transgenic technology

    Author : Maj Hedtjärn; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : ; hypoxia-ischemia; neonatal; brain; inflammation; cytokine; IL-1; IL-18; microglia; gene; microarray;

    Abstract : Hypoxic-ischemic (HI) brain injury remains a common problem encountered during theneonatal period, and it is a major cause of perinatal mortality and long term neurologicalimpairments. After HI, an inflammatory reaction is elicited in the brain, which is believedto contribute to the secondary progression of brain injury. READ MORE