Search for dissertations about: "iga"

Showing result 1 - 5 of 210 swedish dissertations containing the word iga.

2. 1. Intestinal IgA synthesis: Localization and requirements for IgA class switch recombination

   Author : Peter Bergqvist; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IgA; Intestine; Gut associated lymphoid tissue; class switch recombination; CD40; germ free;

   Abstract : Production of IgA at mucosal surfaces is one of the most striking features of the mucosal immune system. Despite that IgA was first discovered in the 1950’s and secretory IgA described in gut secretions and breast milk in the mid 1960’s we still have limited information about the sites and exact requirements for IgA class switch recombination. READ MORE

4. 2. Mucosal immunity in the respiratory tract : The role of IgA in protection against intracellular pathogens

   Author : Ariane Rodríguez; Carmen Fernández; Lennart Hammarström; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucosal immunity; respiratory tract; IgA; intracellular pathogens; Immunology; Immunologi;

   Abstract : The lungs and upper airways are mucosal surfaces that are common site for infection with an enormous variety of inhaled pathogens. Therefore, induction of immune responses in the respiratory tract is crucial for protection against respiratory diseases. One of the pathogens infecting the host via the respiratory tract is Mycobacterium Tuberculosis. READ MORE

5. 3. Studies on streptococcal M proteins. Interactions with IgA and human complement regulators

   Author : Eskil Johnsson; Institutionen för laboratoriemedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; antigenic variation; factor H; C4b-binding protein; Fc-receptor; IgA; Streptococcus pyogenes; M protein; mykologi; virologi; bakteriologi; Mikrobiologi; virology; mycology; bacteriology;

   Abstract : The human pathogenic bacterium Streptococcus pyogenes (group A Streptococcus) expresses several different virulence factors. Of these, the M protein is regarded as one of the most important, because it confers resistance to phagocytosis, allowing the bacterium to multiply in blood. READ MORE

6. 4. Regulation of gut IgA induction by helper T cells

   Author : Inta Gribonika; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucosal immunology; secretory IgA; T regulatory cells; T follicular helper cells; Th17 cells; Peyer s patches; IgA class-switch recombination; germinal centers;

   Abstract : The gut is the largest lymphoid organ in the body. Due to intense and constant exposure to the outside world, it also functions as the most important portal of entry for many pathogens. READ MORE

7. 5. IgA Nephropathy – Mucosal Immunity and Treatment Options

   Author : Hilde Kloster Smerud; Bengt Fellström; Gudjon Kristjansson; Roger Hällgren; Johan W. de Fijter; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IgA nephropathy; mucosal immunity; gastrointestinal sensitivity; food allergens; pharmacological treatment; budesonide; statin; clinical trial; renal transplantation; recurrence; Internal Medicine; Internmedicin;

   Abstract : In the present studies we have explored the link between food hypersensitivity and IgA nephropathy (IgAN) and evaluated treatment options in primary and recurrent disease. Approximately one third of our IgAN patients had a rectal mucosal sensitivity to gluten, as demonstrated by increased local mucosal nitric oxide production and/or myeloperoxidase release after gluten challenge. READ MORE