Search for dissertations about: "igf-i"
Showing result 16 - 20 of 161 swedish dissertations containing the word igf-i.
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16. Hormone concentrations during pregnancy and maternal risk of epithelial ovarian cancer
Abstract : Background: The aim of this thesis was to study the relationship of pre-diagnostic circulating concentrations of sex steroid hormones (androgens, estradiol, 17-hydroxyprogesterone, and progesterone), growth factors (insulin-like growth factor-I (IGF-I), placental growth hormone (GH)), sex hormone binding globulin (SHBG), and anti-Müllerian hormone (AMH) with risk of epithelial ovarian cancer (EOC) overall, and by tumor invasiveness and histology. A longitudinal study was used to assess patterns of hormonal changes during a single pregnancy, and in two consecutive pregnancies. READ MORE
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17. Apoptosis Regulation in Multiple Myeloma
Abstract : Multiple myeloma (MM) is a virtually incurable B cell malignancy of the bone marrow. One important part of tumor progression and an obstacle for successful therapy is resistance to apoptosis. To combat this resistance, the mechanisms of apoptosis and survival in MM must be better defined. READ MORE
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18. Gluten challenge in children with coeliac disease. With special reference to dose dependence and impact on growth markers and growth hormone secretion
Abstract : Coeliac disease is a prevalent food intolerance in both children and adults, in which ingestion of gluten causes inflammation of the small intestine. This inflammation resolves upon gluten withdrawal, and gluten challenge induces relapse of enteropathy in susceptible individuals. READ MORE
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19. Growth Hormone and Gender. Studies in Healthy Adults and in Patients with Growth Hormone Disorders
Abstract : The use of a new, more sensitive immunoassay for growth hormone (GH) revealed that the serum levels in men were lower than expected in sera drawn ambulatory in the morning after an overnight fast and that the gender difference was more than 10 times greater than reported. These observations led to a more thorough study on the impact of gender and sex steroids on the levels of GH and other hormones in ambulatory morning samples and over a 24-hour period. READ MORE
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20. Regulation of apoptosis in human multiple myeloma
Abstract : Multiple myeloma (MM) is a clonal expansion of malignant plasmablasts-plasma cells in the bone marrow. MM is slowly proliferating and an increased resistance to apoptosis may be crucial for the tumor progression. READ MORE