Search for dissertations about: "igf"

Showing result 1 - 5 of 303 swedish dissertations containing the word igf.

  2. 1. Insulin and IGF-I in type 1 diabetes

    Author : Christina Hedman; Claes-Göran Östenson; Linköpings universitet; []
    Keywords : Type I diabetes; IGF-I; IGF system; insulin; insulin analogues; MEDICINE; MEDICIN;

    Abstract : Patients with type I diabetes have alterations in the GH/IGF system with reduced levels of circulating IGF-I, as well as other disturbances in the components of the IGF system.Alterations of both local and circulating IGF-I and its binding proteins (IGFBPs) have been associated with metabolic and vascular manifestations of diabetes and also with atherosclerosis. READ MORE

  4. 2. Early growth, retinopathy of prematurity and insulin-like growth factors in preterm infants

    Author : Eva Engström; Göteborgs universitet; []
    Keywords : Preterm; ROP; nutrition; growth; growth restriction; IGF-I; IGF-II; IGFBP-3;

    Abstract : Aims:Paper I: To perform measurements of the lower leg length (LLL) in preterm infants, compare and evaluate handling error and precision of two instruments, and estimate the time required to show growth.Paper II-IV: To investigate whether low postnatal levels of serum IGF-I are associated with abnormal retinal vessel development. READ MORE

  5. 3. Early effects of castration therapy in non-malignant and malignant prostate tissue

    Author : Nina Ohlson; Pernilla Wikström; Anders Bergh; Pär Stattin; Marja Nevalainen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; human biopsies; androgen ablation; stroma; epithelium; micro-dissection; PSA; IGF-1; IGF-R1; AR; Pathology; Patologi;

    Abstract : Early Effects of Castration Therapy in Non-malignant and Malignant Prostate Tissue BACKGROUND. Androgen ablation, the standard treatment for advanced prostate cancer, results in increased apoptosis, decreased cell proliferation and subsequent involution of the prostate gland. READ MORE

  6. 4. Pathophysiological Mechanisms and Diagnostic Markers in Alzheimer’s Disease

    Author : Joakim Hertze; Klinisk minnesforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; mild cognitive impairment; white matter lesions; brain reserve; blood-brain barrier; angiogenesis; neuroinflammation; neurogranin; YKL-40; VEGF; IGF; ICAM-1; VCAM-1;

    Abstract : Alzheimer’s disease (AD), the most common cause of dementia, is a growing concern. As the life expectancy increases across the globe, the number of affected people is estimated to reach 100 million by 2050. READ MORE

  7. 5. Effects of GH and liver-derived IGF-I on growth and metabolism

    Author : Klara Sjögren; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GH; IGF-I; Insulin; GHRH; Somatostatin; GHS; Body growth; Body composition; Liver; Bone mineral content; Bone mineral density.;

    Abstract : Growth hormone (GH) exerts major effects on body growth and metabolism. Insulin-like growth factor (IGF) is expressed in response to GH and is known to mediate many of the effects of GH. The largest expression of IGF is found in the liver although it is expressed in virtually every tissue of the body. READ MORE