Search for dissertations about: "illumina"

Showing result 1 - 5 of 45 swedish dissertations containing the word illumina.

2. 1. Genomic adaptation and gene-dosage regulation of Drosophila melanogaster cells, and long-read software developments

   Author : Jacob Lewerentz; Per Stenberg; Jan Larsson; Bergman Casey; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Drosophila; cell line; long read; Nanopore; Pacbio; Illumina; cancer; genome evolution; dosage compensation; structural variant; software; bioinformatics;

   Abstract : Cells are the vehicles that allows genetic code to proliferate in the world, taking on various forms – as illustrated by the tree of life. The cell features are determined by the manufacturing of proteins, a process that has its blueprints encoded as genes in the genome. READ MORE

4. 2. Massively parallel analysis of cells and nucleic acids

   Author : Julia Sandberg; Joakim Lundeberg; Nader Pourmand; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Massively parallel sequencing; 454; Illumina; multiplex amplification; whole genome amplification; single cell; polyguanine; flow-cytometry;

   Abstract : Recent proceedings in biotechnology have enabled completely new avenues in life science research to be explored. By allowing increased parallelization an ever-increasing complexity of cell samples or experiments can be investigated in shorter time and at a lower cost. READ MORE

5. 3. Composition and dynamics of the bacterial community in aerobic granular sludge reactors

   Author : Enikö Barbara Szabo; Chalmers tekniska högskola; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; qPCR; sequencing batch reactors; microbial community composition; T-RFLP; functional groups; Illumina MiSeq; wastewater; aerobic granular sludge; nitrogen removal; population dynamics;

   Abstract : The aerobic granular sludge (AGS) technology is probably the future standard for wastewater treatment, due to its low footprint and low energy consumption. Although achieving granulation is usually not a challenge anymore, our understanding of the community assembly during start-up, and of the microbial ecology of these reactors in general, is incomplete. READ MORE

6. 4. Advancing Evolutionary Biology: Genomics, Bayesian Statistics, and Machine Learning

   Author : Tobias Andermann; Göteborgs universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; computational biology; bioinformatics; phylogenetics; neural networks; NGS; target capture; Illumina sequencing; fossils; IUCN conservation status; extinction rates;

   Abstract : During the recent decades the field of evolutionary biology has entered the era of big data, which has transformed the field into an increasingly computational discipline. In this thesis I present novel computational method developments, including their application in empirical case studies. READ MORE

7. 5. Phylogenetic Relationships, Biogeography and Species Delimitation: A case study on southern African Silene (Caryophyllaceae)

   Author : Ntwai A. Moiloa; Göteborgs universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Elisanthe; Illumina sequencing; Multispecies coalescent model; NGS; Phylogenetics; Phylogeography; species-trees; STACEY; target-capture;

   Abstract : The primary aim of this thesis was to explore the phylogenetic relationships and historical biogeography of African members of the plant genus Silene (Caryophyllaceae), with special focus on the eight native southern African taxa. Three loci (the nuclear ribosomal internal transcribed spacer region, and the rps16 and matK regions from the plastid genome) generated using traditional Sanger sequencing were used to infer the phylogenetic positions of African taxa, while sequence data from 28 low copy nuclear loci were generated using the target capture method to explore shallow phylogenetic relationships within southern African taxa. READ MORE