Search for dissertations about: "immune risk phenotype"

Showing result 11 - 15 of 95 swedish dissertations containing the words immune risk phenotype.

  2. 11. Biliary epithelial cells, the immune system and PSC pathogenesis

    Author : Lena Berglin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Primary sclerosing cholangitis (PSC) is a chronic, inflammatory liver disease that leads to destruction of the bile duct system. PSC is strongly associated with inflammatory bowel disease, and PSC patients have an increased risk of developing malignancies, especially cholangiocarcinoma (CCA). READ MORE

  4. 12. Improving stroke risk prediction and individualised treatment in carotid atherosclerosis

    Author : Eva Karlöf; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Unstable carotid atherosclerosis causes stroke, but methods to identify patients and lesions at risk are lacking. Currently, this risk estimation is based on measurements of stenosis and neurological symptoms, which determines the therapy of either medical treatment with or without carotid endarterectomy. READ MORE

  5. 13. Mapping the immune landscape in solid tumors : implications for immunotherapy

    Author : Emelie Foord; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Our cells are programmed with various safety mechanisms to avoid transformation into tumor cells. In case these fail, we have a guarding immune system ready to recognize and eliminate these cells. Despite these safety measurements, cancer is one of the leading causes of death worldwide. The tumor cells find ways to escape the immune system. READ MORE

  6. 14. Norovirus and rotavirus susceptibility : studies from a Nicaraguan birth cohort

    Author : Yaoska Reyes; Johan Nordgren; Lennart Svensson; Miren Iturriza-Gómara; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Norovirus; Rotavirus; Birth cohort; Gastroenteritis; Incidence; Children; Secretor; Immune response.;

    Abstract : Norovirus and rotavirus are major causes of pediatric acute gastroenteritis (AGE). It is estimated that norovirus is responsible for ~20% of all diarrheal diseases in children worldwide and causes approximately 200,000 deaths each year, mostly in young children and the elderly. READ MORE

  7. 15. Experimental models of pediatric brain tumors. Establishment, immunophenotyping and clinical implications

    Author : Emma Sandén; Neurokirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatric Brain Tumor; Experimental model; Immunotherapy; Immune monitoring; Medulloblastoma;

    Abstract : Brain tumors are the most common solid tumors in children. Current treatment protocols fail in 25% of patients and are associated with significant long-term adverse effects in survivors. READ MORE