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Showing result 1 - 5 of 408 swedish dissertations matching the above criteria.
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1. Effects of Complement Opsonization of HIV on Dendritic Cells : and Implications for the Immune Response
Abstract : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. READ MORE
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2. Immune-to-Brain Signaling in Fever : The Brain Endothelium as Interface
Abstract : Fever is a brain-regulated elevation of body temperature that occurs in response to infectious and non-infectious stimuli. During inflammatory episodes, circulating cytokines that are released by activated immune cells, trigger the induction of cyclooxygenase (COX)-2 in the ventromedial preoptic area of the hypothalamus (the thermoregulation center). READ MORE
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3. Signaling pathways in Drosophila immunity
Abstract : Drosophila relies on innate immunity to protect itself from its hostile environment throughout its life cycle. Despite the remarkable progress in understanding many aspects of Drosophila immunity, there are still big gaps in our knowledge. READ MORE
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4. SIGNALING MECHANISMS IN SEPSIS-INDUCED IMMUNE DYSFUNCTION
Abstract : Sepsis and subsequent organ failure remain the major cause of mortality in intensive care units in spite of significant research efforts. The lung is the most vulnerable organ affected by early hyper-inflammatory immune response in septic patients. READ MORE
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5. Prostaglandin E2 in immune-to-brain signaling
Abstract : Upon immune-challenge, signaling from the immune system to the brain triggers an array of central nervous responses that include fever, anorexia, hyperalgesia and activation of the hypothalamus-pituitary adrenal axis. These symptoms are dependent on cytokines produced at the site of inflammation. READ MORE