Search for dissertations about: "immune system model"

Showing result 16 - 20 of 446 swedish dissertations containing the words immune system model.

  2. 16. Candida albicans adaption to host microenvironments drives immune evasion

    Author : José Pedro Lopes; Constantin F. Urban; Alistair Brown; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fungi; candida albicans; neutrophils; mast cells; immune evasion; mycoses; infectious diseases; immunologi; Immunology; Infectious Diseases; infektionssjukdomar; Molecular Immunology; molekylär immunologi;

    Abstract : Immunosuppressed patients are frequently afflicted with severe mycoses caused by opportunistic fungal pathogens. Besides being a commensal colonizing predominantly skin and mucosal surfaces, Candida albicans is the most common human fungal pathogen. READ MORE

  4. 17. On Neuroimmunology and Brain Function: Experimental and Clinical Studies

    Author : Nina Strenn; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immune system; mental disorders; polymorphisms; depression; autism; bipolar disorder; SSRI; S100B; 5-HTR2A; Flinders sensitive line;

    Abstract : The immune system has been implicated in the mechanisms underlying many psychiatric disorders. Immune mediators are expressed in the central nervous system (CNS) not only in response to harmful stimuli, but also in a constitutive manner, and serve as important plasticity factors during development. READ MORE

  5. 18. Interaction between biomaterials and innate immunity with clinical implications

    Author : Shan Huang; Kristina Nilsson Ekdahl; Charlotte Dahle; Linnéuniversitetet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Complement system; contact system; blood; biomaterials; biocompatibility; in vitro screening; iC3; dialysis;

    Abstract : Today there is an increasing clinical demand and expectation of patients for biomaterials, which underscores the importance of discovering the correlations between biomaterials and biological systems, especially blood. When an artificial material makes contact with blood, the first event is a rapid adsorption of plasma protein on the material surface, on top of which the innate immune system is triggered, with potentially detrimental consequences. READ MORE

  6. 19. On the etiology and pathogenesis of systemic lupus erythematosus with special reference to environmental factors

    Author : Anders Bengtsson; Reumatologi och molekylär skelettbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi; Skeleton; Risk factors; Human parvovirus B19; Immune complex; Disease activity; Interferon-alpha; SLE; Retrovirus;

    Abstract : Systemic lupus erythematosus (SLE) is a complex autoimmune disease in which environmental factors interact with genetic factors in the development of the disease process and evolution of clinical manifestations. In this thesis both exogenous factors and host factors were investigated, as well as important immunopathological aspects including involvement of immune complex (IC), the complement system and interferon-alpha (IFN-α). READ MORE

  7. 20. B cell deviations and type 1 diabetes in the NOD mouse

    Author : Mia Sundström; Kristina Lejon; Susanna Cardell; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Type 1 diabetes; Autoimmunity; NOD mouse; Idd; TACI; Immune response; Immune complex; immunologi; Immunology;

    Abstract : Type 1 diabetes (T1D) is a chronic autoimmune disease in which the insulin producing β-cells in the pancreatic islets of Langerhans are selectively attacked by the immune system. The β-cells are destroyed resulting in a reduced or eliminated insulin production, which in turn lead to a high blood glucose level. READ MORE