Search for dissertations about: "immunoassay"

Showing result 6 - 10 of 114 swedish dissertations containing the word immunoassay.

  2. 6. Development of Methods for Measuring Protein C Inhibitor and Antithrombin: Use of Monoclonal Antibodies against the Reactive Center Loop-Inserted Forms of the Serpins

    Author : Margareta Kjellberg; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; monoclonal antibody; latent antithrombin; immunoassay; cleaved PCI; cleaved antithrombin; Antithrombin; APC-PCI complex;

    Abstract : Protein C inhibitor (PCI) and antithrombin (AT) are serine protease inhibitors (serpins) that are involved in the regulation of coagulation. Like other inhibitory serpins, PCI and AT adopt different structural conformations that are related to their functions. READ MORE

  4. 7. Immuno-affinity interactions in sample preparation and analysis

    Author : Madalina Tudorache; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; immuno supported liquid membrane ISLM extraction; sample preparation; immunoassay; immuno-affinity interaction; antibody; Analytical chemistry; Analytisk kemi;

    Abstract : Immuno-affinity interactions (antibody-antigen) belong, together with enzyme-inhibitor/substrate/coenzyme; oligosaccharide-lectin; DNA/RNA-protein interactions etc, to the class of bio-recognition. Immuno-affinity is widely used for analysis in immunoassays with numerous applications in a variety fields (i.e. READ MORE

  5. 8. Metal Binding Tags - Characterisation, Use in Bioseparation and Applications of Green Fluorescent Fusion Proteins

    Author : Florent Bernaudat; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Proteiner; enzymologi; enzymology; E. coli; Immobilised metal ion affinity chromatography; Affinity tags; Green fluorescent protein; Surface plasmon resonance; Genetic engineering; Screening; Proteins; Immunoassay; Biotechnology; Bioteknik;

    Abstract : Most of the recombinant proteins produced nowadays are fused to affinity tags, in order to facilitate their purification through affinity chromato-graphy. Out the different tags available, poly-histidine tags are among the most commonly used and can help purification through immobilised metal ion affinity chromatography (IMAC). READ MORE

  6. 9. GH Secretion in children. Methodological aspects of determining immunoreactive and bioactive isoforms

    Author : Chatarina Löfqvist; Göteborgs universitet; []
    Keywords : Growth hormone; immunoassay; cross-reactivity; standard; antibody; insulin-like growth factor 1; reference values;

    Abstract : A child's hormone-dependent growth is dependent on multiple factors, although linear growth is closely associated with levels of growth hormone (GH) secretion. As GH in serum exists in several isoforms, some of which may not be identified by immunoassay, possible alterations in the secretion of these different isoforms in childhood may influence growth and/or metabolism. READ MORE

  7. 10. Proteomic strategies for blood biomarker development in rare dystrophinopathies

    Author : Camilla Johansson; Cristina Al-Khalili Szigyarto; Ola Söderberg; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Duchenne muscular dystrophy; Becker muscular dystrophy; proteomics; affinity-proteomics; biomarkers; DIA-MS; SRM-MS; immunoassay; suspension bead arrays; Duchenne muskeldystrofi; Becker muskeldystrofi; proteomik; affinitetsproteomik; biomarkörer; DIA-MS; SRM-MS; immunoassay; suspension bead array; Biotechnology; Bioteknologi;

    Abstract : Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are two rare genetic disorders of the family dystrophinopathy. They are both caused by the lack of, or reduced production of, the protein dystrophin. READ MORE