Search for dissertations about: "immunoassays"

Showing result 6 - 10 of 86 swedish dissertations containing the word immunoassays.

  2. 6. Development and evaluation of immunoassays for complement diagnostics

    Author : Kerstin Sandholm; Kristina Nilsson Ekdahl; Ingvar Ryden; Linnéuniversitetet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immune assays; complement diagnostics; xMAP-technology; C1q; preanalytical factors; method validation; Immunologi; Immunology;

    Abstract : Laboratory analyses of human body fluids play an important role in clinical diagnosis. This thesis comprises projects in which various immune assays have been developed and evaluated as complement diagnostics in both plasma and cerebrospinal fluid (CSF). READ MORE

  4. 7. DNA-Assisted Immunoassays for High-Performance Protein Analyses

    Author : Junhong Yan; Masood Kamali-Moghaddam; Ulf Landegren; Christer Wingren; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proximity ligation assay; magnetic beads; conjugation; phosphorylation; affinity binder; protein complexes; recombinant binder; sensitivity; specificity; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : Proteins play important roles in most cellular functions, such as, replication, transcription regulation, signal transduction, for catalyzing chemical reaction, etc. Technologies developed to identify proteins rely either on observing their own properties such as charge, size, mass to charge ratio or sequence composition; or on using affinity reagents that recognize specific protein targets. READ MORE

  5. 8. New Bioanalytical Approaches, Magneto Immunoassays and SIRE Technology Based Biosensors

    Author : Kirstin Kriz; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemical technology; Biokemisk teknik; antigens; superparamagnetic nanoparticles; magnetic inductance transducer; competitive magneto immunoassay; enzymes; metabolites; differential measurements; SIRE; biosensor;

    Abstract : This thesis presents two new technologies, SIRE technology based biosensors and magneto immunoassays, which can be used for bioanalytical applications. One of the main problems associated with biosensor technology is the instability of the recognition element since it is of biological origin and thus, has a limited lifetime. READ MORE

  6. 9. Sample Handling Techniques in Biological and Environmental Applications Emphasizing Biomolecular Recognition and MALDI-TOF MS

    Author : Patrik Önnerfjord; Reumatologi och molekylär skelettbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein identification; microchip IMER; microdispensing; MALDI-TOF MS; fluorescence polarization; flow immunoassay; pesticide immunoassays; phenol biosensor; restricted access media; SPE; Analytical chemistry; Analytisk kemi;

    Abstract : The use of restricted access media and other stationary phases for clean-up and trace enrichment of environmental samples coupled on-line to liquid chromatography using diode array detection as well as thermospray MS is described. This on-line configuration was compared with commercially available ELISAs for the determination of triazines in complex matrices, showing superior precision and accuracy with the chromatographic method. READ MORE

  7. 10. Enzymatic and Immunological Detection Principles for Environmental and Biological Applications

    Author : Elisabeth Burestedt; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; interleukin-8; D-ammino acids; carbon paste; flow immunoassays; Amperometric biosensors; phenols; Analytisk kemi;

    Abstract : The aim of the thesis was to develop new analytical detection principles based on enzymatic and immunological reactions for sensitive, selective, cost-effective and high sample through-put detection devices. The thesis presents the basic elements and reaction paths necessary for the construction and development of enzyme based amperometric biosensors and immunoassays. READ MORE