Search for dissertations about: "immunohistochemistry IHC"

Showing result 1 - 5 of 71 swedish dissertations containing the words immunohistochemistry IHC.

  1. 1. Prognostic and Predictive Factors in Bladder Cancer

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Tammer Hemdan; Uppsala universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bladder cancer; BCG; cisplatin; STMN1; emmprin; survivin; CCTα; biomarker; immunohistochemistry; IHC; tissue microarray; TMA;

    Abstract : Bladder cancer is a potentially curable malignancy; however in regards to the state of current therapy regimens, a plateau has been reached in both the non-muscle and muscle invasive types. To obtain effective treatment, and consequently a decreased mortality, it has become imperative to test and understand aspects affecting therapy response. READ MORE

  2. 2. Proteomic Analysis of Urinary Bladder Cancer Aiming for Novel Biomarkers

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Mårten Lindén; Uppsala universitet.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; urine; APOE; FGB; GAL1; LRG1; POLR1E; SERPINA1; STMN1; TOP2A; biomarker; diagnostic biomarker; prognostic biomarker; predictive biomarker; mass spectrometry; western blot; dot blot; immunohistochemistry; IHC; tissue microarray; TMA; urothelium; antibody; antibody-based; urinblåsecancer; biomarkör; diagnos; prognos; urin; proteomik; masspektrometri; immunohistokemi; antikroppar; Molecular Biology; Molekylärbiologi; Molekylär medicin; Molecular Medicine;

    Abstract : Urinary bladder cancer is a heterogeneous disease appearing in different forms, e.g. non-muscle invasive and muscle invasive. For all variants, the expression of proteins is interesting to analyze for diagnostic, predictive, prognostic and drug targeting purposes, since it reflects the altered gene expression causing the cancer. READ MORE

  3. 3. Validation of antibodies for protein profiling A study using immunohistochemistry on tissue microarrays

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Linda Paavilainen; Uppsala universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibody validation; monospecific antibodies; protein profiling; immunohistochemistry; tissue microarrays; western blot; fixatives; MEDICINE Morphology; cell biology; pathology Pathology; MEDICIN Morfologi; cellbiologi; patologi Patologi; Pathology; patologi;

    Abstract : The field of proteomics has rapidly expanded due to the completion of the human genome sequence. This thesis validates affinity-purified monospecific antibodies of polyclonal origin, for protein profiling in a broad spectrum of normal tissues and cells. READ MORE

  4. 4. Quantitative immunochemistry in tissue sections : With special reference to urinary bladder carcinoma

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Kenneth Wester; Uppsala universitet.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Urinary bladder carcinoma; immunohistochemistry; quantification; image analysis; Genetik; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik; Pathology; patologi;

    Abstract : Urinary bladder carcinoma affects about 2 000 people in Sweden every year. It is a heterogeneous disease and for adequate treatment decisions, prognostic tools are needed. Many of these are based on immunohistochemistry (MC) and hampered by poorly reproducible methodologies and subjective evaluations. READ MORE

  5. 5. Prognostic factors in soft tissue sarcoma. Tissue microarray for immunostaining, the importance of whole-tumor sections and time-dependence

    University dissertation from Oncology, Lund

    Author : Jacob Engellau; Lunds universitet.; Lund University.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; growth pattern; time-dependence; P-glycoprotein Pgp ; CD44; β-catenin; cyclin A; bcl-2; p53; Ki-67; immunohistochemistry IHC ; whole-tumor sections; tissue microarray TMA ; Soft tissue sarcoma; prognostic factors; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : Popular Abstract in Swedish Maligna mjukdelstumörer, så kallade mjukdelssarkom, utgör hos vuxna en ovanlig tumörform som uppkommer i kroppens stödjevävnader. Till dessa räknas muskler, fett, bindväv, slemsäckar samt kärl och nerver som försörjer dessa vävnader. READ MORE