Search for dissertations about: "immunohistokemi"

Showing result 6 - 10 of 18 swedish dissertations containing the word immunohistokemi.

  2. 6. JNK/c-Jun Signaling and Peripheral Nerve Regeneration

    Author : Charlotta Lindwall; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; neuropsykologi; neurofysiologi; neurophysiology; Neurologi; neuropsychology; Neurology; Djurfysiologi; Animal physiology; JNK; signal transduction; nerve regeneration;

    Abstract : The events associated with axonal injury in the peripheral nervous system (PNS) have been described in detail. However, the molecular mechanisms underlying the regenerative response, or neuronal cell death, following axonal injury are poorly understood. READ MORE

  4. 7. Identification, Validation and Implementation of Blastemal Biomarkers in Wilms Tumour

    Author : Daniel Sehic; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wilms Tumour; Nephroblastoma; SIX1; Blastema; biomarker; Immunochemisty; Immunohistochemestry;

    Abstract : The aim of this thesis has been to establish biomarkers for the blastemal element in Wilms tumour (WT) – the most common paediatric kidney cancer. Blastema is, together with epithelium and stroma, one of the three common histological elements of WT. WTs dominated by blastema after preoperative chemotherapy are classified as high risk tumours. READ MORE

  5. 8. Nitric oxide in central nervous structures associated with water balance and micturition

    Author : Anders Nylén; Lunds universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacological sciences; spinal projections; True Blue; cystometry; circumventricular organs; paraventricular nucleus; supraoptic nucleus; NADPH diaphorase; immunohistochemistry; oxytocin; 8-arginine-vasopressin; hypothalamus; rat; micturition; nitric oxide; water balance; neuronal nitric oxide synthase; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Abstract : The role of nitric oxide (NO) in the central control of water balance and micturition has not yet been established. In the present thesis, where female rats were used, neuronal NO synthase (nNOS) distribution was studied in structures of the central nervous system known to be associated with the above mentioned control. READ MORE

  6. 9. The involvement of the TNF-alpha system in skeletal muscle in response to marked overuse

    Author : Lina Renström; Sture Forsgren; Per Stål; Håkan Alfredson; Eva Ekblad; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TNF-alpha; TNFR1; TNFR2; muscle damage; myositis; peritendinous tissue; tendinopathy;

    Abstract : Painful conditions having the origin within the musculoskeletal system is a common cause for people to seek medical care. Between 20-40% of all visits to the primal care in Sweden are coupled to pain from the musculoskeletal system. Muscle pain and impaired muscle function can be caused by muscles being repetitively overused and/or via heavy load. READ MORE

  7. 10. The impact of glucotoxicity on pancreatic β-cell function

    Author : Sarheed Jabar Muhammed; Islet cell physiology; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cAMP PKA system; iNOS; Type 2 diabetes; GSIS; PDE; GK rat; ZDF fa fa rat; GPR40; VDAC1; VDAC2; GSK-3β; ChREBP; TXNIP; resveratrol.;

    Abstract : Type 2 diabetes mellitus is connected with elevated plasma glucose levels which negatively influence β-cells and cause impaired glucose-stimulated insulin secretion (GSIS). The aim of present thesis was to investigate the impact of long-term hyperglycemia on the pancreatic islet β-cell function. READ MORE