Search for dissertations about: "immunology gene"
Showing result 1 - 5 of 185 swedish dissertations containing the words immunology gene.
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1. Defining the genetics of systemic autoimmunity in mouse models of lupus
Abstract : Systemic Lupus Erythematosus (SLE) is a chronic multi-organ autoimmune disease considered a prototype for autoantibody and immune complex-mediated tissue injury. Although autoantibodies against a wide diversity of self-antigens are characteristically found in this disease, an important hallmark is the presence of autoantibodies to nuclear antigens. READ MORE
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2. Immune complex induced IgG1-rheumatoid factor production
Abstract : Rheumatoid arthritis is a chronic crippling disease mainly characterised by inflammation in the joints. Most patients with rheumatoid arthritis are seropositive, i.e. have increased serum levels of antibodies against the constant part of IgG, so called rheumatoid factors (RF). READ MORE
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3. Molecular and cellular mechanisms in the development of IDDM in non-obese diabetic mice
Abstract : Insulin dependent diabetes mellitus (IDDM) is a disease caused by autoimmune destruction of the insulin producing b cells in the pancreas. The leukocytic infiltration into the b cell islets preceding disease is called insulitis. READ MORE
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4. The PD-1 pathway and the complement system in systemic lupus erythematosus
Abstract : Autoimmune diseases occur in up to 3-5% of the general population and represent a diverse collection of diseases with regards to clinical manifestations. The unifying factor of autoimmune diseases is tissue and organ damage as a result of an immune response mounted against self-antigens. READ MORE
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5. Immunologic aspects of the pathogenesis of human onchocerciasis
Abstract : Onchocerciasis, or river blindness, is a parasitic disease that affects more than 20 million people globally. The induction of pathology is directly related to the presence and destruction of the microfilarial stages (mf) of this filarial nematode. READ MORE
