Search for dissertations about: "immunotherapy subcutaneous"

Showing result 1 - 5 of 10 swedish dissertations containing the words immunotherapy subcutaneous.

  1. 1. Cancer Immunotherapy A Preclinical Study of Urinary Bladder Cancer

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Christina Ninalga; Thomas Tötterman; Magnus Essand; Timothy Ratliff; [2006]
    Keywords : Medicine; immunotherapy; bladder carcinoma; cancer; CpG ODNs; Adenoviral vector; CD40L; TRANCE; Lymphotactin; IL2; IL15; Medicin;

    Abstract : Bacillus Calmette Guérin (BCG), or attenuated Mycobacterium bovis, is the gold standard of immunotherapy in the clinic to treat superficial bladder cancer. However, setbacks remain due to a high recurrence rate, side effects, and BCG-refractory disease. READ MORE

  2. 2. Adenovirus-mediated CD40 Ligand Immunotherapy of Prostate and Bladder Cancer

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Helena Dzojic; Uppsala universitet.; [2007]
    Keywords : Medicine; immunotherapy; gene therapy; prostate cancer; bladder cancer; adenoviral vector; CD40 ligand; promoter; PPT; TSTA; depsipeptide FK228; TRAMP-C2; Medicin;

    Abstract : Cancer immunotherapy aims at reversing the immunosuppressive tumor environment and enhancing anti-tumor immunity. This thesis comprises studies on murine models for prostate (TRAMP-C2) and bladder (MB49) cancer with the aim to explore if the introduction of an adenoviral vector expressing CD40 ligand (AdCD40L) can induce anti-tumor immune responses. READ MORE

  3. 3. The Multiple Faces of Genetically-Modified T Cells Potential Applications in Therapy

    University dissertation from Uppsala : Uppsala universitet

    Author : Victoria Hillerdal; Magnus Essand; Johanna Olweus; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer immunotherapy; genetically engineered T cells; chimeric antigen receptor; T cell receptor; antigen-specific T cells; immunotherapy; Immunologi; Immunology; Klinisk immunologi; Clinical Immunology;

    Abstract : In this PhD thesis the potential of T-cells as therapy for disease are explored. The applications of genetically modified T-cells for treatment of cancer and autoimmune disease; the functionality and optimal activation of T-cells are discussed. READ MORE

  4. 4. Treatment of malignant tumors with histamine. Clinical and experimental studies

    University dissertation from Göteborg

    Author : Magnus Rizell; Göteborgs universitet.; Gothenburg University.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; histamine; histamine H2-receptors; microdialysis; pharmacokinetics; ; neoplasm; sarcoma; melanoma; immunotherapy;

    Abstract : For metastatic melanoma there is no treatment to prolong life. Histamine has in experimental tumors shown tumor inhibiting effects. In vitro, histamine inhibit phagocyte-derived radical oxygen species to protect natural killer and cytotoxic T-lymphocytes. READ MORE

  5. 5. Adverse Reactions after Vaccination and Allergen-Specific Immunotherapy: Contact Allergy to Aluminium and Itching Nodules

    University dissertation from Eva Netterlid

    Author : Eva Netterlid; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Patch test; Itching nodules; Contact allergy; ASIT; Aluminium; Allergen-specific immunotherapy; Adverse event; Parental reports; vaccination;

    Abstract : The aim of the work presented in this thesis was to investigate two different types of adverse reactions, persistent itching nodules and contact allergy to aluminium, after immunization with aluminium-containing vaccines and aluminium-containing allergen extracts used for allergen-specific immunotherapy (ASIT). The first paper describes active parental reporting of adverse events (AEFIs) after a booster dose of diphtheria-tetanus vaccine (DT). READ MORE