Search for dissertations about: "imputation"

Showing result 11 - 15 of 34 swedish dissertations containing the word imputation.

  1. 11. Statistical Methods for Genome Wide Association Studies

    Author : Malin Östensson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Genome Wide Association Studies; gene-gene interactions; Genotype imputation; allele sharing; haplotype sharing; Single Nucleotide Polymorphism; Celiac Disease; haplotype sharing;

    Abstract : This thesis focus on various statistical methods for analyzing Genome Wide Association data. The thesis include four papers, three of them considers the analysis of complex traits, and the last one a method for analyzing mendelian traits. READ MORE

  2. 12. Bayesian Cluster Analysis : Some Extensions to Non-standard Situations

    Author : Jessica Franzén; Daniel Thorburn; Jukka Corander; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cluster analysis; Clustering; Classification; Mixture model; Gaussian; Bayesian inference; MCMC; Gibbs sampler; Deviant group; Longitudinal; Missing data; Multiple imputation; Statistics; Statistik; Statistics; statistik;

    Abstract : The Bayesian approach to cluster analysis is presented. We assume that all data stem from a finite mixture model, where each component corresponds to one cluster and is given by a multivariate normal distribution with unknown mean and variance. READ MORE

  3. 13. Female sex hormones and health outcomes in women with specific focus on asthma

    Author : Guo-Qiang Zhang; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; asthma; Bayesian estimation; case-control; causal inference; estrogens; female sex hormones; hormonal contraceptives; menarche; menopausal hormone therapy; menopause; meta-analysis; multiple imputation; progestogens; research reproducibility; robust variance estimation; systematic review; umbrella review; women;

    Abstract : In humans, gender differences exist across a wide spectrum of diseases. For instance, women are more likely to develop Sjogren’s syndrome, systemic lupus erythematosus, and autoimmune thyroid disease compared to men. READ MORE

  4. 14. Improving methods for Genome Wide Analysis of Coeliac Disease

    Author : Malin Östensson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Genome Wide Association Studies; Coeliac Disease; Genotype Imputation; Genome Wide Association Studies;

    Abstract : .... READ MORE

  5. 15. A computational and statistical framework for cost-effective genotyping combining pooling and imputation

    Author : Camille Clouard; Carl Nettelblad; Christine Baes; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The information conveyed by genetic markers, such as single nucleotide polymorphisms (SNPs), has been widely used in biomedical research to study human diseases and is increasingly valued in agriculture for genomic selection purposes. Specific markers can be identified as a genetic signature that correlates with certain characteristics in a living organism, e. READ MORE