Search for dissertations about: "in mice"

Showing result 1 - 5 of 2570 swedish dissertations containing the words in mice.

  2. 1. Neurodevelopmental Consequences of Exposure to Paracetamol (Acetaminophen) and Related Drugs : Experimental studies in mice

    Author : Gaëtan Philippot; Robert Fredriksson; Vesna Jevtovic-Todorovic; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; paracetamol acetaminophen ; developmental neurotoxicology; delta9-tetrahydrocannabinol THC ; ibuprofen; endocannabinoid system; neonatal mice; brain growth spurt; behavior; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi;

    Abstract : Paracetamol (acetaminophen) is the analgesic pharmaceutical most commonly used during pregnancy and early life. While therapeutic doses of paracetamol are considered harmless during these periods, recent findings in both humans and rodents suggest a link between developmental exposure to paracetamol and behavioral consequences later in life. READ MORE

  4. 2. Growth regulation in sarcomas : studies in vivo and in cell culture

    Author : Avni Abdiu; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Sarcomas are malignant tumors of mesenchymal origin, and can arise in soft-tissue and in bones. It has been suggested that the abnormal growth regulation in sarcoma cells may be due to an autocrine mechanism, in which the cells are stimulated by an endogenous production of growth factors. READ MORE

  5. 3. The expression and function of CD25 B cells in man and in mice

    Author : Amu Sylvie; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B cell; CD25; rheumatoid arthritis; systemic lupus erythematosus; mice;

    Abstract : B cells play an important role both in the physiology and pathology of immune responses by production of antibodies, cytokines and by presentation of antigens. It has been shown that human CD25 expressing B cells display a mature phenotype, perform better as antigen presenting cells but secrete less immunoglobulins. READ MORE

  6. 4. The Role of Microvascular Pericytes in the Generation of Pro-fibrotic Connective Tissue Cells : Investigations in vitro and in Reactive Tissues in vivo

    Author : Jakob Karén; Christian Sundberg; Gunilla Westergren-Thorsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pericyte fibroblast differentiation fibrosis; Biochemistry; Biokemi; Microbiology; Mikrobiologi; Cell biology; Cellbiologi; Medical Biochemistry; Medicinsk biokemi; Cellforskning; Cell Research; Mikrobiologi; Microbiology;

    Abstract : Pericytes are cells of mesenchymal origin located on the abluminal side, juxtapositioned to the endothelial cells in capillaries, venules and small arterioles. They are important for maintaining vessel integrity in resting tissues as well as the formation and stabilization of new vessels. READ MORE

  7. 5. THE ANGIOGENIC RESPONSE IN HYPOXIC HEART. Experimental studies in mice

    Author : Fei Tian; Göteborgs universitet; []
    Keywords : hypoxia; angiogenesis; mice; endoglin; SUMO; PDI;

    Abstract : Coronary artery disease is the leading cause of death in the western world today. Although induction of angiogenesis would appear to be an ideal therapeutic strategy, clinical trials of proangiogenic factors have proved disappointing. READ MORE