Search for dissertations about: "in vitro gel"

Showing result 1 - 5 of 97 swedish dissertations containing the words in vitro gel.

2. 1. Growth regulation in sarcomas : studies in vivo and in cell culture

   Author : Avni Abdiu; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : Sarcomas are malignant tumors of mesenchymal origin, and can arise in soft-tissue and in bones. It has been suggested that the abnormal growth regulation in sarcoma cells may be due to an autocrine mechanism, in which the cells are stimulated by an endogenous production of growth factors. READ MORE

4. 2. Studies of Eosinophil Cationic Protein (ECP) in vivo and in vitro : Impact of Genetic and Posttranslational Modifications

   Author : Jenny Eriksson; Per Venge; Agneta Trulson; Ester Boix; Uppsala universitet; []
   Keywords : Biomedicine; Eosinophil granulocyte; granular protein; ECP; gene polymorphism; cytotoxicity; SELDI-TOF MS; glycosylation; molecular and functional heterogeneity; fibrosis; Biomedicin;

   Abstract : Eosinophil granulocytes are tissue dwelling leukocytes that are implicated in host defence, particularly against helminthic parasites; they also participate in most inflammatory disorders. Although eosinophils have important roles in host defence mechanisms, their actions can also be harmful to the host as in the allergic inflammation where lung epithelium is destructed due to the release of toxic granule proteins. READ MORE

5. 3. Development and characterization of an in vitro method for interaction studies between polymers and pharmaceuticals : Aiding in the development of new drug delivery systems

   Author : Marcus Wanselius; Per Hansson; Magnus Bergström; Susanna Abrahmsén-Alami; Christian Pedersen; Anna Fureby; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microgels; Subcutaneous administration; Drug delivery; Microfluidics; In vitro methodology; Method development; Biopharmaceuticals; Amphiphilic drugs; Polyelectrolytes; Hyaluronic acid; Peptides; Farmaceutisk fysikalisk kemi; Pharmaceutical Physical Chemistry;

   Abstract : Polymers are a group of macromolecules used in formulations of pharmaceuticals, one example being the delivery system DC Bead™. Further, some of the most abundant and for drug delivery important constituents of the subcutaneous tissue are charged polymers (polyelectrolytes), e.g. collagen, hyaluronic acid, and chondroitin sulfate. READ MORE

6. 4. In vitro and in vivo studies of salivary films at solid/liquid interfaces

   Author : Ida Svendsen; Malmö högskola; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; saliva; proteins; adsorption; ellipsometry; gel electrophoresis;

   Abstract : A conditioning film, the pellicle, of which many salivary proteins areimportant constituents, covers the surfaces present in the mouth. The pellicleforms in a selective adsorption process, and it has protective and lubricatingfunctions as well as an influence on the adherence of oral microbes thatultimately leads to the development of dental plaque. READ MORE

7. 5. Evolving the Methodology for Detection of Primary DNA Damage : Development, adaptation and assessment of the single cell gel electrophoresis (comet) assay

   Author : Erik Bivehed; Björn Hellman; Hanna Karlsson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Comet assay; DNA damage; DNA strand breaks; Flash-comet; Genotoxicity; In vitro; Single cell gel electrophoresis; Polymerase assisted DNA damage assay PADDA ; TK6 cells; UCDAS; U937 cells; Toxikologi; Toxicology; Farmaceutisk vetenskap; Pharmaceutical Science;

   Abstract : Deoxyribonucleic acid (DNA) is one of the most important molecules in nature. It is the fundamental carrier of evolutionary information and constitutes the genetic blueprint of all living organisms. Being the sole source of information, it is vital for the cell to transmit the correct genetic information from generation to generation. READ MORE