Search for dissertations about: "in vivo dosimetry"

Showing result 16 - 20 of 35 swedish dissertations containing the words in vivo dosimetry.

  2. 16. In vivo dosimetry of some important industrial chemicals by measurement of their reaction products with hemoglobin

    Author : Hermes Licea Pérez; Åke Bergman; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical Biology; fysikalisk biologi;

    Abstract : Hemoglobin adduct measurements provide a useful tool for the development of models for risk assessment of chemicals. The measurements can be used to identify reactive metabolites and to determine the in vivo doses of these metabolites. READ MORE

  4. 17. In vivo imaging of the cannabinoid CB1 receptor using positron emission tomography

    Author : Garth Terry; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The actions of marijuana (cannabis) are mediated by receptors (primarily the cannabinoid CB1 receptor) that have unusually high density and wide distribution in brain. In addition to mediating the effects of exogenous drugs like cannabis, these receptors also receive signals from endogenous cannabinoids (endocannabinoids), which modulate the release of several other neurotransmitters. READ MORE

  5. 18. PET and MR imaging in prostate cancer

    Author : Kristina Sandgren; Tufve Nyholm; Joakim Jonsson; Camilla Thellenberg-Karlsson; Lennart Blomqvist; Heidi Lyng; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PET; PSMA; MRI; PET MRI; imaging; prostate cancer; intraprostatic tumour detection; radiofysik; radiation physics;

    Abstract : The current risk assessment of prostate cancer (PC) relies on histopathological samples from biopsies and clinical variables such as prostate-specific antigen (PSA). However, this comes with uncertainties and in some cases it can be challenging to separate patients who would benefit from radical treatment and those who would not. READ MORE

  6. 19. Theranostic Targeting of GRPR and PSMA in Prostate Cancer

    Author : Ayman Abouzayed; Anna Orlova; Ulrika Rosenström; Anzhelika Vorobyeva; Bogdan Mitran; Cristina Müller; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; gastrin-releasing peptide receptor GRPR ; prostate-specific membrane antigen PSMA ; nuclear medicine; molecular imaging; radiotracers; theranostics; Farmaceutisk vetenskap; Pharmaceutical Science; Oncology; Onkologi;

    Abstract : This thesis is based on five original articles that investigated the theranostics of prostate cancer by gastrin-releasing peptide receptor (GRPR) and prostate-specific membrane antigen (PSMA) targeting. GRPR and PSMA are two extensively evaluated prostate cancer cell markers due to their overexpression in the majority of prostate cancer samples. READ MORE

  7. 20. Development and comparison of in vitro toxicity methods for nanoparticles : Focus on lung cell exposure

    Author : Siiri Latvala; Karine Elihn; Hanna Karlsson; Lennart Möller; Hannu Norppa; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Applied Environmental Science; tillämpad miljövetenskap;

    Abstract : Concerns for the toxic effects of airborne nanoparticles have been raised along with the increasing production of nanostructured materials. However, the health risks of nanoparticle exposure are currently not fully understood. The most commonly used techniques to study nanoparticle toxicity, both in vivo and in vitro, have several limitations. READ MORE