Search for dissertations about: "in vivo protection"

Showing result 1 - 5 of 168 swedish dissertations containing the words in vivo protection.

2. 1. Helicobacter pylori and Gastric Protection Mechanisms : An in vivo Study in Mice and Rats

   Author : Johanna Henriksnäs; Lena Holm; Lars Engstrand; Erik Persson; Lars Fändriks; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; mucus gel layer; mucosal blood flow; mucus thickness; intra-vital microscopy; laser-Doppler flowmetry; pH-sensitive microelectrode; nitric oxide; Helicobacter pylori; bicarbonate secretion; mouse model; Fysiologi; Physiology; Fysiologi;

   Abstract : The stomach is frequently exposed to hazardous agents and to resist this harsh environment, several protective mechanisms exist. Of special interest is the gastric pathogen Helicobacter pylori which causes gastritis, ulcers and cancer but the mechanism leading to these diseases are still unclear. However it is very likely that H. READ MORE

4. 2. Gastric gland luminal pressure and mucosal protection : An in vivo study in the anesthetized rat

   Author : Ingrid Synnerstad; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; acid secretion; bicarbonate; epithelial cell surface pH; gastric gland; muscularismucosa; micropuncture; mucosal blood flow; mucus gel thickness; omeprazole; permeability; prostaglandins; ranitidine; rat; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

   Abstract : The driving force for creation of channels in gastric mucus, for acid and pepsin transport, ismost probably the hydrostatic pressure generated within the gastric gland lumen. The aim ofthis study was to investigate the origin and regulation of the glandular pressure. READ MORE

5. 3. Short and long-term effects of exposure to low dose and low dose rate of gamma radiation : using in vitro and in vivo models

   Author : Traimate Sangsuwan; Siamak Haghdoost; Eva Forssell-Aronsson; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Low dose; Low dose rate; High dose rate; Ionizing radiation; Adaptive response; Senescence; Premature senescence; Oxidative stress; Drosophila embryo; Mutation; DNA repair; molekylär biovetenskap; Molecular Bioscience;

   Abstract : Assessment of human health risks from exposure to ionizing radiation (IR) is mainly based on the extrapolation of results from epidemiological studies on populations exposed to relatively high doses and often at high dose rates (HDR). Risk estimates after exposure to low doses and in particular at low dose rates (LDR) remain controversial due to a lack of epidemiological evidence. READ MORE

6. 4. Acid transport through gastric mucus : A study in vivo in rats and mice

   Author : Mia Phillipson; Lena Holm; Henrik Sjövall; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; gastric acid; pH-sensitive microelectrode; mucus; mucosal blood flow; nitric oxide; intravital microscopy; laser Doppler flowmetry; Fysiologi; Physiology; Fysiologi; Physiology; fysiologi;

   Abstract : The gastric mucosa is frequently exposed to endogenously secreted hydrochloric acid of high acidity. Gastric mucosal defense mechanisms are arranged at different levels of the gastric mucosa and must work in unison to maintain its integrity. READ MORE

7. 5. Toll-like receptors in airway inflammation in vitro and in vivo

   Author : Ida von Schéele; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : During evolution a variety of solutions has been developed by different living organisms in order to protect itself from invading potential pathogens and particles. Protection of the host is essential for its survival and involves efficient recognition and elimination of potential pathogens. READ MORE