Search for dissertations about: "in vivo."

Showing result 1 - 5 of 3163 swedish dissertations containing the words in vivo..

  1. 1. Growth regulation in sarcomas : studies in vivo and in cell culture

    University dissertation from Linköping : Linköpings universitet

    Author : Avni Abdiu; Linköpings universitet.; Linköpings universitet.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Abstract : Sarcomas are malignant tumors of mesenchymal origin, and can arise in soft-tissue and in bones. It has been suggested that the abnormal growth regulation in sarcoma cells may be due to an autocrine mechanism, in which the cells are stimulated by an endogenous production of growth factors. READ MORE

  2. 2. Studies on glial fibrillary acidic protein (GFAP) in human glioma cells : in vitro and in vivo

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Erik Bongcam-Rudloff; Uppsala universitet.; [1994]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  3. 3. Development of Methods for Assessing Unbound Drug Exposure in the Brain In vivo, in vitro and in silico

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Markus Fridén; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood-brain barrier; Drug transport; Tissue distribution; Transporters; Pharmacokinetics; PHARMACY Other pharmacy; FARMACI Övrig farmaci; PHARMACY Biopharmacy; FARMACI Biofarmaci; PHARMACY Pharmaceutical pharmacology; FARMACI Farmaceutisk farmakologi; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Abstract : The blood-brain barrier is formed by tightly joined capillary cells with transporter proteins and acts as to regulate the brain concentration of nutrients as well as many drugs. When developing central nervous system drugs it is necessary to measure the unbound drug concentration in the brain, i.e. the unbound brain exposure. READ MORE

  4. 4. The Role of Microvascular Pericytes in the Generation of Pro-fibrotic Connective Tissue Cells Investigations in vitro and in Reactive Tissues in vivo

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Jakob Karén; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pericyte fibroblast differentiation fibrosis; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi; MEDICINE Microbiology; immunology; infectious diseases Microbiology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; Medical Biochemistry; Medicinsk biokemi; Cellforskning; Cell Research; Mikrobiologi; Microbiology;

    Abstract : Pericytes are cells of mesenchymal origin located on the abluminal side, juxtapositioned to the endothelial cells in capillaries, venules and small arterioles. They are important for maintaining vessel integrity in resting tissues as well as the formation and stabilization of new vessels. READ MORE

  5. 5. Regulation of Renal Hyaluronan in Water Handling Studies in vivo and in vitro

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Sara Stridh; Uppsala universitet.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kidney; water balance; fluid handling; diabetes; nephropathy; ACE fetopathy; reabsorption; hyaluronic acid; glycosaminoglycan; GAG; extracellular matrix; mTOR; rapamycin; streptozotocin;

    Abstract : Hyaluronan (HA) is a negatively charged extracellular matrix (ECM) component with water-attracting properties. It is the dominating ECM component in the renal medullary interstitium, where the amount changes in relation to hydration status: it increases during hydration and decreases during dehydration. READ MORE