Search for dissertations about: "in-vivo evaluation"
Showing result 1 - 5 of 285 swedish dissertations containing the words in-vivo evaluation.
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1. Lipid peroxidation in vivo : Evaluation and application of methods for measurement
Abstract : Lipid peroxidation is thought to be an important factor in the pathophysiology of a number of diseases and in the process of ageing, but its measurement in vivo has been difficult. The aim of this thesis was to evaluate methods for measurement of lipid peroxidation in vivo that are suitable for clinical investigations, and to apply these methods in animal and human studies investigating basal conditions and situations associated with increased lipid peroxidation. READ MORE
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2. Radiolabelled Oligonucleotides for Evaluation of in vivo Hybridisation Utilising PET Methodology
Abstract : Antisense oligonucleotides (ODN) may interfere in gene expression on the basis of hybridising to its complementary messenger RNA (mRNA) sequence in the cell thereby preventing the synthesis of the peptide. Therefore, these ODNs may be potential drugs to treat human diseases by “knocking down” the expression of responsible genes or correcting the maturation process of mRNA in the field called antisense therapy. READ MORE
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3. Wear and Fixation of the acetabular component : in vivo evaluation of different polyethylenes and modes of fixation in total hip arthroplasty
Abstract : Polyethylene wear and micromotion of the implant play an important role in multifactorial etiology of osteolysis leading to aseptic loosening of the acetabular components. Despite excellent results in primary total hip arthoplasty in a 10-15 year perspective there are still unsolved problems. READ MORE
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4. Mechanisms of Osseointegration: Experimental Studies on Early Cellular and Molecular Events in vivo
Abstract : The early cellular and molecular activities determining the early tissue response and bone formation at bone/implant interface are not fully understood. The general aim of the current thesis was to develop a model for studying the early molecular and cellular activities in different bone types, and in response to different implant surface properties. READ MORE
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5. In Vivo Evaluation of Skeletal Muscle Morphological and Mechanical Properties using Medical Imaging
Abstract : Skeletal muscles are soft tissues that play an important role in maintaining body posture and enabling movements through force generation. The force-generating capacity is associated with the morphological and mechanical properties of the muscle. READ MORE