Search for dissertations about: "indirect-response model lithium pharmacodynamics pharmacokinetics gastrointestinal absorption gastrointestinal motility loperamide erythromycin antidiuretic effect desmopressin overhydration vasopressin analogue F992 interaction Pharmacological sciences pharmacognosy pharmacy toxicology Farmakologi farmakognosi farmaci toxikologi"

Found 1 swedish dissertation containing the words indirect-response model lithium pharmacodynamics pharmacokinetics gastrointestinal absorption gastrointestinal motility loperamide erythromycin antidiuretic effect desmopressin overhydration vasopressin analogue F992 interaction Pharmacological sciences pharmacognosy pharmacy toxicology Farmakologi farmakognosi farmaci toxikologi.

  1. 1. Pharmacokinetic and pharmacodynamic analysis of antidiuretic peptides

    Author : Torbjörn Callréus; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lithium; indirect-response model; pharmacodynamics; pharmacokinetics; gastrointestinal absorption; gastrointestinal motility; loperamide; erythromycin; antidiuretic effect; desmopressin; overhydration; vasopressin analogue F992 ; interaction; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Abstract : The clinical pharmacology of desmopressin and a new vasopressin analogue (F992) was investigated in healthy human subjects. The common procedure of overhydration of healthy volunteers when studying the antidiuretic effect of a drug, may affect the pharmacokinetics, in particular the volumes of distribution. READ MORE