Search for dissertations about: "indole alkaloids"
Showing result 1 - 5 of 7 swedish dissertations containing the words indole alkaloids.
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1. Synthesis of Indole Alkaloids and Development of New Methodology
Abstract : This thesis describes our efforts towards the total synthesis of natural products and the development of a newmethodology to afford a synthetically important scaffold.Chapter 2 outlines our efforts towards the total synthesis of a marine natural product, perophoramidine as wellas our completed synthesis of dehaloperophoramidine. READ MORE
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2. Synthetic studies of marine indole alkaloids and related systems
Abstract : This thesis is mainly focussed oil the synthesis of marine indole alkaloids and related systems, many of which display interesting biological activities. In the first part of this thesis we could establish and confirm the stucture of barettin and 8,9dihydrobarettin, isolated from the marine sponge Geodia baretti. READ MORE
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3. New Arylation Strategies Based on Organomain Group Reactivity
Abstract : The work in this thesis describes the development of new heteroarylation methodology based on transition metal-catalysed C-H functionalisation and the properties of organomain group compounds. The underlying reaction mechanisms and reactivity patterns of the (hetero)arene substrates are also investigated. READ MORE
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4. Syntheses of some tri- and tetracyclic heterocycles containing an indole moiety
Abstract : This thesis deals with the development of new synthetic methods leading to fused tri- and tetracyclic heterocycles, many of which have interesting biological activity such as antiviral and DNA intercalating properties. The reactions between isatins and 2-aminobenzylamine in acetic acid can give, depending on the conditions, either complex spirooxindoles or indolo[3,2-c]quinolin-6-ones. READ MORE
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5. Synthesis of indolocarbazoles, bisindoles and related sulfur containing systems
Abstract : This thesis is focussed mainly on the synthesis and reactions of various indolocarbazoles, bisindoles and related sulfur containing systems, all possessing structural features present in many biologically active, natural or synthetic compounds. In the first part, synthetic routes towards the planar, pentacyclic ring systems of indolo[2,3-c]earbazole and indolo[3,2-a]carbazole are described. READ MORE