Search for dissertations about: "infection mechanism"

Showing result 1 - 5 of 321 swedish dissertations containing the words infection mechanism.

2. 1. The biology of filamentous phage infection - implications for display technology

   Author : Fredrik Karlsson; Institutionen för immunteknologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biotechnology; Bioteknik; infection mechanism; selective infection; TolA; Escherichia coli; pIII; Filamentous phage; Phage display technology;

   Abstract : Phage display technology is a biotechnological tool that can be used to obtain molecules/reagents able to discriminate between target molecules. Reagents with such features can be used in diverse settings like biological chemistry, diagnostics and in therapeutic applications. READ MORE

4. 2. Antimicrobial peptides in the treatment of infectious and inflammatory conditions : Preclinical studies of mechanism of action, efficacy, and safety

   Author : Camilla Björn; RISE; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial peptides; AMPs; innate immunity; infection; inflammation; mechanism of action; efficacy; safety; antimicrobial resistance; antibiotic resistance; Antimicrobial peptides; AMPs; innate immunity; infection; inflammation; mechanism of action; efficacy; safety; antimicrobial resistance; antibiotic resistance;

   Abstract : The rapid emergence of antibiotic-resistant microbes worldwide and the urgent need of new antimicrobial agents have stimulated interest in antimicrobial peptides (AMPs) as new therapeutics for treatment of infectious diseases. AMPs are present in all living species and constitute an important part of the innate immune system in multicellular organisms, including humans. READ MORE

5. 3. Contact activation on bacterial surfaces - a virulence mechanism

   Author : Kristin Persson; Infektionsmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; General biomedical sciences; Biomedicinska vetenskaper allmänt ; sepsis; infection; S. aureus; S. typhimurium; E. coli; curli; fibrinopeptides; fibrinogen; Coagulation; contact system;

   Abstract : Life-threatening conditions from bacterial infections are a major clinical problem. During a severe infection, the host responds by a massive release of pro-inflammatory mediators together with a systemic activation of systems such as the coagulation, fibrinolytic, and complement systems. READ MORE

6. 4. Coxsackievirus B3 Infection and Host Defence Responses Change the Metabolism of PBDE

   Author : Magnus Lundgren; Nils-Gunnar Ilbäck; Hans Tjälve; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Coxsackievirus; environmental pollutants; PBDE; cytokines; chemokines; metabolism; infection; tissue distribution; toxicology; virology; immunology; Toxicology; Toxikologi; Virology; Virologi; Medicine; medicin;

   Abstract : It has been suggested that the rising amounts of chemicals in the environment may affect host resistance and increase susceptibility to infections. Studies have also shown that infections can change the toxicity of pollutants. READ MORE

7. 5. Multiple functions of YopN in the Yersinia pseudotuberculosis type III secretion system : from regulation to in vivo infection

   Author : Sarp Bamyaci; Åke Forsberg; Edouard Galyov; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Type III secretion system; Yersinia; YopN; virulence; phagocytosis; mouse infection; secretion kinetics;

   Abstract : The type 3 secretion systems (T3SSs) are virulence mechanisms used by various Gram-negative bacteria to overcome the host immunity. They are often target-cell contact induced and activated. Activation results in targeting of virulence effector substrates into host cells. READ MORE