Search for dissertations about: "infectious diseases Microbiology"

Showing result 11 - 15 of 63 swedish dissertations containing the words infectious diseases Microbiology.

  2. 11. Outer membrane proteins of Yersinia pestis : Ail and OmpA

    Author : Sara Celinda Schesser Bartra; Hans Wolf-Watz; Virginia Miller; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia pestis; outer membrane proteins; Ail; ompA; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar; immunologi; Immunology; mikrobiologi; Microbiology; Infectious Diseases; infektionssjukdomar;

    Abstract : A vast number of studies have been completed on the virulence determinants of Yersinia spp.; however, the focus of many of these studies has been on the virulence plasmid and the plasmid-encoded Type three secretion system. Nevertheless, many chromosomal genes whose products are directly involved in virulence have also been identified. READ MORE

  4. 12. Study of Resistance in Hepatitis C Virus Prior to Treatment with Direct Acting Antivirals

    Author : Midori Kjellin; Johan Lennerstrand; Nina Weis; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatitis C; HCV; DAA; RAS; resistance-associated substitution; baseline resistance; NS5A; NS3; SVR; Medical Virology; Medicinsk virologi; Mikrobiologi; Microbiology; Infektionssjukdomar; Infectious Diseases;

    Abstract : The rapid advancement of Hepatitis C (HCV) treatment presents a great challenge to clinicians in optimising therapy for their patients. Genotype (GT), efficacy, side-effects, drug combinations and treatment durations must be tailored to individual patients, considering comorbidities, degree of fibrosis, adherence and antiviral resistance. READ MORE

  5. 13. Advancing isothermal nucleic acid amplification tests : Towards democratization of diagnostics

    Author : Felix Neumann; Mats Nilsson; Paul Yager; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; molecular diagnostics; infectious diseases; point-of-care; digital quantification; fluorescence detection; rolling circle amplification; padlock probes; microfluidic enrichment; Biochemistry; biokemi;

    Abstract : Modern healthcare is the result of scientific advancement across disciplines and has enabled us to understand the rationale behind many diseases and how to treat or cure them; but still a myriad of unanswered questions remains. Especially infectious diseases play an important role in healthcare as they pose a constant threat for global health and well-being. READ MORE

  6. 14. Optimization of Colistin Dosage in the Treatment of Multiresistant Gram-negative Infections

    Author : Matti Karvanen; Otto Cars; Lena E Friberg; Vincent H Tam; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colistin; CMS; Pharmacology; Pharmacokinetics; PKPD; Antibiotics; Combination therapy; Pharmacometrics; Dosing regimens; Antibiotic resistance; Infectious Diseases; Infektionssjukdomar;

    Abstract : As multidrug resistance in Gram-negative bacilli increases, the old antibiotic colistin has rapidly gained attention as one of few last line treatment options in the form of colistin methanesulfonate (CMS), which is hydrolyzed to colistin both in vitro and in vivo. There is a dearth of knowledge on fundamental aspects of colistin, including pharmacokinetics and optimal dosing regimens. READ MORE

  7. 15. Studies on hereditary C2 deficiency: Frequent occurrence of severe infections, atherosclerosis and rheumatological manifestations

    Author : Göran Jönsson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; serology; Immunology; mykologi; bakteriologi; virologi; Mikrobiologi; mycology; Complement; Complement C2 deficiency; Infectious diseases; Atherosclerosis; SLE; Autoantibodies; GM allotypes; Immunodeficiency state; Medicine human and vertebrates ; Medicin människa och djur ; Microbiology; virology; bacteriology; Immunologi; serologi; Infections; Infektioner;

    Abstract : The complement system is a part of the innate immunity and is essential in the defence against microorganisms. Hereditary C2 deficiency (C2D) is one of the most common complement deficiency states with an estimated prevalence of 1:20,000 in persons of Western descent. READ MORE