Search for dissertations about: "infectivity"
Showing result 1 - 5 of 72 swedish dissertations containing the word infectivity.
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1. Novel inhibitors of Chlamydia trachomatis virulence
Abstract : Chlamydia trachomatis is an obligate intracellular bacterium that infects over 100 million people globally every year. Chlamydia infections can be persistent, cause infertility and blindness, adding an economical burden in the healthcare systems. READ MORE
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2. Physics of Viral Infectivity: Energetics of Genome Ejection
Abstract : All viruses that infect bacteria, plant, or animal cells involve a genome (RNA or DNA) that is encapsidated by a rigid protein shell. After delivery of the viral genome into the host cell, new capsid proteins, which are encoded by viral DNA or RNA, are expressed and self-assembled into new viral capsids. READ MORE
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3. Factors Influencing Evolution to Antimalarial Drug Resistance in Plasmodium falciparum in Sudan and The Gambia
Abstract : Drug resistance is a major obstacle to management and control of malaria and currently progressing at a rapid rate across Africa. This thesis has examined factors influencing evolution of resistant P. falciparum at two sites in Africa, including parasite migration, cross mating and fitness cost of resistance. READ MORE
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4. Altering HIV-1 envelope glycoprotein maturation and its effects on viral infectivity
Abstract : HIV-1 is dependent on its envelope glycoprotein (Env) to initiate infection. Env binds to cellular receptors and mediate the following fusion of the viral envelope with the cell plasma membrane. READ MORE
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5. Effect of the tri-peptide glycyl-prolyl-glycine amide on HIV-1 replication
Abstract : The human immunodeficiency virus type 1 (HIV-1) is the etiological agent responsible for AIDS worldwide. The aim of this thesis was to evaluate the anti-HIV-1 activity of short peptides and to investigate their mode of inhibition. READ MORE