Search for dissertations about: "inhibitory neurotransmission"

Showing result 1 - 5 of 35 swedish dissertations containing the words inhibitory neurotransmission.

  2. 1. Nicotine sensitization and loss of inhibitory control. Role of serotonin

    Author : Peter Olausson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nicotine; Amphetamine; Locomotor activity; Inhibitory control; Dopamine; Serotonin; Sensitization; Nucleus accumbens; Elevated plus-maze;

    Abstract : Drug dependence is a devastating disorder present in all parts of the world. It is manifested by craving and a general loss of control over the drug intake and the life situation, ultimately leading to compulsive use of the addictive drug at the expense of normal behavioral patterns. READ MORE

  4. 2. Functional Imaging of Spinal Locomotor Networks

    Author : Chetan Nagaraja; Klas Kullander; Gilad Silberberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Central pattern generators; two-photon microscopy; locomotor rhythm; multiple rhythmicities; inhibitory neurotransmission; Neuroscience; Neurovetenskap;

    Abstract : Movement is necessary for the survival of most animals. The spinal cord contains neuronal networks that are capable of motor coordination and of producing different movements. In particular, a very reduced neuronal network in the spinal cord can produce simple rhythmic outputs even in the absence of descending or sensory inputs. READ MORE

  5. 3. Studies on nitric oxide in autonomic neurotransmission

    Author : Caroline Olgart; Karolinska Institutet; Karolinska Institutet; []
    Keywords : acetylcholine; autonomic neurotransmission; botulinum toxin; colon; guinea pig; ileum; intestine; nitric oxide; rat; tachykinin.;

    Abstract : The aim of the present thesis was to study nitric oxide (NO) as a mediator in autonomic neurotransmission in the enteric nervous system, including studies on the mechanism for neuronal release of NO, as well as the effects of NO on intestinal smooth muscle and enteric neurones. Furthermore, the signal transduction pathway for the evoked effects of NO and nitrergic neurotransmission were investigated. READ MORE

  6. 4. Galanin : a modulator of serotonin neurotransmission : relevance for depression

    Author : Haleh Razani; Karolinska Institutet; Karolinska Institutet; []
    Keywords : galanin; 5-HT1A receptors; 5-HT; 8-OH-DPAT; fluoxetine; robalzotan; passive avoidance; microdialysis; mRNA; KD values; Bmax values; depression;

    Abstract : Galanin is widely distributed throughout the central nervous system with multiple and diverse biological roles. In the rat, galanin-like immunoreactivity is expressed in a population of5-hydroxytryptamine (5-HT, serotonin) neurons in the dorsal raphe (DR) with extensive projections to the forebrain areas e.g., hippocampus. READ MORE

  7. 5. Nicotine sensitization and the effects of extended withdrawal - behavioral, neurochemical and electrophysiological studies in the rat

    Author : Julia Morud; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Abstinence; Dopamine; Elevated plus-maze; GABA; Inhibitory control; Nicotine; Nucleus accumbens; Sensitization;

    Abstract : Tobacco use is one of the primary factors for global burden of disease and often results in life-long nicotine addiction, only a small percentage users are able to maintain cessation. The life-long addiction together with a high relapse risk might be connected to drug-induced altered neural circuits. READ MORE