Search for dissertations about: "innate immune response"
Showing result 1 - 5 of 357 swedish dissertations containing the words innate immune response.
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1. Effects of Complement Opsonization of HIV on Dendritic Cells : and Implications for the Immune Response
Abstract : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. READ MORE
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2. Haemophilus influenzae adhesins and the innate immune response
Abstract : Haemophilus influenzae is a human specific Gram-negative respiratory tract pathogen. Encapsulated H. influenzae strains exist in six different serotypes a-f, of which type b (Hib) is the most virulent. Hib is protected by the polysaccharide capsule when invading the blood circulaton and may cause diseases such as meningitis and epiglottitis. READ MORE
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3. Innate immune cell response in sepsis
Abstract : Leukocyte recruitment is known to be a key feature at sites of inflammation and important in the combat against infectious agents. However, the mechanisms of leukocyte recruitment in the pulmonary microvasculature in response to local and systemic inflammation remain elusive. READ MORE
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4. Regulatory aspects of innate immune responses
Abstract : Activation of innate immunity is regulated by a variety of signaling molecules within the immune cells. The present thesis was aimed to improve our understanding of innate signaling mechanism and their possible use as bio-indicators of exposure and disease. READ MORE
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5. Innate immune response in human endothelial cells : characterization and regulation of E-selectin, ICAM-I and cytokine expression and the role of Staphylococcus aureus
Abstract : Endothelial cells located on the vessel walls play an important role in inflammation. In response to cytokines or other inflammatory mediators such as microorganisms, endothelial cells express cell adhesion molecules such as E-selectin and ICAM-1 that are involved in binding circulating leukocytes to the endothelium. READ MORE