Search for dissertations about: "inorganic complexes"

Showing result 1 - 5 of 92 swedish dissertations containing the words inorganic complexes.

2. 1. Vanadate and Peroxovanadate Complexes of Biomedical Relevance : A speciation approach with focus on diabetes

   Author : András Gorzsás; Lage Pettersson; Carlos F. G. C. Geraldes; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Inorganic chemistry; vanadium; hydrogen peroxide; lactate; citrate; phosphate; alanyl serine; picolinic acid; speciation; formation constants; equilibrium; solution structure; potentiometry; NMR 51V; 31P; 13C; 1H ; Oorganisk kemi; Inorganic chemistry; Oorganisk kemi; oorganisk kemi; Inorganic Chemistry;

   Abstract : Diabetes mellitus is one of the most threatening epidemics of modern times with rapidly increasing incidence. Vanadium and peroxovanadium compounds have been shown to exert insulin–like actions and, in contrast to insulin, are orally applicable. However, problems with side–effects and toxicity remain. READ MORE

4. 2. Open-framework Structures Built by Inorganic Clusters : Synthesis and Characterization

   Author : Hong Chen; Junliang Sun; Xiaodong Zou; Thomas E Albrecht-Schmitt; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Open-framework; germanates; vanadoborates; aluminoborates; germanosilicates; crystal structure; hydrothermal synthesis; crystal X-ray diffraction; rotation electron diffraction; powder X-ray diffraction; Inorganic Chemistry; oorganisk kemi;

   Abstract : Novel open-framework germanates and vanadoborates, which are constructed from typical types of clusters, have been synthesized based on different strategies. The crystal structures are solved by using single crystal X-ray diffraction (SXRD) technique or by combined techniques. READ MORE

5. 3. Reactions of Model and Anticancer Active Platinum(IV/II) Complexes - A Kinetic and Mechanistic Study

   Author : Kelemu Lemma; Kemiska institutionen; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Model Pt II complexes; Anticancer active Pt IV compounds; Cisplatin; Rescue agents; L-Ascorbic acid; Thiol; Substitution; Kinetics and mechanism; Electron transfer; Inorganic chemistry; Oorganisk kemi;

   Abstract : In this thesis reductions of model and anticancer active Pt(IV) complexes with thiols and ascorbic acid and substitution reactions of cisplatin and model Pt(II) complexes with S-donor nucleophiles (rescue agents) have been investigated using stopped-flow and UV/VIS spectrophotometry. Glutathione (GSH) reduction of the anticancer active Pt(IV) compounds t- and c-[PtCl4(cha)(NH3)] (cha = cyclohexylamine), t-[PtCl4(thiazole)(NH3)] and c-[PtCl4(NH3)2] at 25 oC was observed to be very fast. READ MORE

6. 4. Interactions of Anticancer Active Platinum(II) Complexes with DNA

   Author : Johan Kjellström; Bröstcancer-genetik; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Inorganic chemistry; polyelectrolyte; medium effects; salt dependence; DSC; CD; HPLC; oligonucleotide; hairpin; DNA; anticancer active platinum II compounds; kinetics; mechanism; Oorganisk kemi; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

   Abstract : The kinetics and mechanism for interactions of the anticancer active platinum(II) complexes cis-[PtCl2(NH3)2)], cis-[PtCl2(NH3)(c-C6H11NH2)], and trans-[PtCl2-(NH3)(quinoline)] with DNA have been studied using a combination of HPLC, circular dichroism (CD), UV/vis spectroscopy, and differential scanning calorimetry (DSC). Reactions of the monoaqua forms (charge = +1) of these complexes with single-stranded DNA oligonucleotides, typically between 13-17 bases long, were found to depend on i) the composition of the reaction medium, ii) the exact nature and location of the platination target, and iii) on the DNA structure. READ MORE

7. 5. Chemical Processes at the Water-Manganite (γ-MnOOH) Interface

   Author : Madeleine Ramstedt; Staffan Sjöberg; Per Persson; Lars Lövgren; Steven A. Banwart; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Inorganic chemistry; manganite; γ-MnOOH; mineral surface; acid-base properties; adsorption; Cd II ; N- phosphonomethyl glycine; glyphosate; PMG; surface complex; dissolution; disproportionation; XPS; EXAFS; infrared spectroscopy; SEM; AFM; potentiometry; electrophoresis; Oorganisk kemi; Inorganic chemistry; Oorganisk kemi; oorganisk kemi; Inorganic Chemistry;

   Abstract : The chemistry of mineral surfaces is of great importance in many different areas including natural processes occurring in oceans, rivers, lakes and soils. Manganese (hydr)oxides are one important group to these natural processes, and the thermodynamically most stable trivalent manganese (hydr)oxide, manganit (γ-MnOOH), is studied in this thesis. READ MORE