Search for dissertations about: "insulin action"

Showing result 1 - 5 of 153 swedish dissertations containing the words insulin action.

  1. 1. Regulation of intracellular signaling events that modulate insulin action

    University dissertation from Göteborg

    Author : Silvia Gogg; Göteborgs universitet.; Gothenburg University.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insulin; insulin resistance; EGF; Gab 1; insulin receptor substrate; PI3-kinase; Thiazolidinediones; PPARã; insulin signaling; glucose transport; adipose tissue; â-cell.;

    Abstract : Insulin regulates several mechanisms of fundamental importance to the body involving glucose, fat andprotein metabolism. Insulin resistance in skeletal muscle, liver and adipose tissue promotes an increaseddemand for insulin secretion. READ MORE

  2. 2. Fat cell insulin resistance an experimental study focusing on molecular mechanisms in type 2 diabetes

    University dissertation from Umeå : Folkhälsa och klinisk medicin

    Author : Frida Renström; Umeå universitet.; [2007]
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; adipocyte; insulin signaling; insulin; glucose; IRS-1; glucose uptake; insulin resistance; typ 2 diabetes; serum; VETERINARY MEDICINE Medicine; VETERINÄRMEDICIN Medicin;

    Abstract : The aim of the present thesis was to further increase our understanding of mechanisms contributing to and maintaining cellular insulin resistance in type 2 diabetes (T2D). For this reason, the effects of high glucose and insulin levels on glucose transport capacity and insulin signaling, with emphasis on insulin receptor substrate 1 (IRS-1) were assessed in fat cells. READ MORE

  3. 3. Adipocyte phosphatases and the antilipolytic action of insulin

    University dissertation from Svante Resjö, BMC, C11, SE-221 84 LUND, SWEDEN

    Author : Svante Resjö; Lund University.; Lunds universitet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein phosphorylation; protein purification; adipose tissue; PP2A; protein phosphatase; PDE3B; phosphodiesterase 3B; Insulin signalling; antilipolysis; Klinisk biologi; Clinical biology; PKB; protein kinase B;

    Abstract : Adipose tissue is the main site of energy storage of the body and an important endocrine organ. Knowledge of the regulation of fat metabolism and the endocrine factors secreted by the adipocyte is crucial for the understanding of diseases such as obesity and diabetes. Insulin is the main antilipolytic hormone. READ MORE

  4. 4. Assessment and Treatment of Impaired Insulin- Secretion and Action in Type 2 Diabetes

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Mozhgan Dorkhan; Lund University.; Lunds universitet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes; insulin secretion; glucagon test; insulin resistance; insulin glargine; insulin tolerance test; thiazolidinediones; natriuretic peptides; adiponectin; thyroid associated ophthalmopathy; proinsulin;

    Abstract : Type 2 diabetes (T2D) is a disease characterised by varying degrees of defect in insulin secretion and insulin sensitivity and associated with increased morbidity and mortality. Optimal glycaemic control reduces the progression of diabetic complications. READ MORE

  5. 5. Insulin Polymorphism Crystallographic Characterization of Insulin Microcrystals

    University dissertation from Molecular Biophysics, Lund University

    Author : Mathias Norrman; Lund University.; Lunds universitet.; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Strukturkemi; Structure chemistry; biomatematik; protein crystallography; X-ray powder diffraction; Bioinformatics; medical informatics; microcrystals; Bioinformatik; Molekylär biofysik; Molecular biophysics; biomathematics biometrics; medicinsk informatik; insulin;

    Abstract : Insulin is a protein needed for the uptake of glucose from the circulating blood. In absence of sufficiently high insulin levels in the body or when the cells have a reduced sensitivity for insulin a disease state referred to as diabetes occurs. Treatment of diabetes generally requires daily injections of exogenous insulin. READ MORE