Search for dissertations about: "insulin resistance in type in type 2 diabetes mellitus"
Showing result 1 - 5 of 67 swedish dissertations containing the words insulin resistance in type in type 2 diabetes mellitus.
-
1. Search for Type 2 Diabetes Susceptibility Genes Using Multiple Approaches
Abstract : Type 2 diabetes mellitus is a multifactorial disorder characterized by chronic hyperglycemia resulting from pancreatic dysfunction and insulin resistance. It is a common disorder with a complex pattern of inheritance, likely to reflect the influence of multiple genetic and environmental factors on the diabetes risk. READ MORE
-
2. Dissecting the role of micro-RNAs in diabetes
Abstract : The role of miRNAs in pancreatic islets and β-cell function and in the development of diabetes in human and rodents have been investigated in this thesis. Dicer1 was specifically deleted in vivo in pancreatic β-cells under the RIP-promoter in mice. READ MORE
-
3. Genetic and Metabolic Markers for the Development of Diabetes after Gestational Diabetes Mellitus
Abstract : The aims of this work were to determine the prevalence of postpartum diabetes among women with gestational diabetes mellitus (GDM) in a prospective study 5 years postpartum; to characterize these women according to insulin secretion, insulin sensitivity, autoimmunity and genetics; and to identify possible markers and predictors for the development of manifest diabetes. The subjects were recruited through a regional screening programme in which oral glucose tolerance tests (OGTTs) are routinely offered to all pregnant women. READ MORE
-
4. Semi-mechanistic models of glucose homeostasis and disease progression in type 2 diabetes
Abstract : Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by consistently high blood glucose, resulting from a combination of insulin resistance and reduced capacity of β-cells to secret insulin. While the exact causes of T2DM is yet unknown, obesity is known to be a major risk factor as well as co-morbidity for T2DM. READ MORE
-
5. Genetic and immunological risk factors of gestational diabetes mellitus
Abstract : Gestational diabetes mellitus (GDM) is a heterogeneous disorder that is defined as carbohydrate intolerance with onset or first recognition during pregnancy. Impaired beta-cell function and insulin resistance are the hallmarks of GDM. READ MORE