Search for dissertations about: "insulin-like growth factor 1"

Showing result 6 - 10 of 155 swedish dissertations containing the words insulin-like growth factor 1.

  2. 6. Experimental studies on the effects of insulin-like growth factor I and glucocorticoids on bone metabolism

    Author : Kenneth B. Jonsson; Uppsala universitet; []
    Keywords : Medical sciences; Bone; bone resorption; glucocorticoids; insulin-like growth factor I; osteoblasts; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Osteoporosis is a major cause of disability among patients that are dependent on glucocorticoids in the treatment of inflammatory disease. The pathogenesis behind this side effect is complex, involving dysregulation of hormonal systems and direct effects on bone cells. READ MORE

  4. 7. The insulin-like growth factor system : effects of circulating proteases

    Author : Sara Gustafsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The insulin-like growth factor-I and -II (IGF-I/-II) are peptide hormones important for growth and metabolism. They stimulate cell proliferation and differentiation and inhibit apoptosis. In addition, they have insulin-like effects on glucose and amino acid metabolism. READ MORE

  5. 8. Insulin-like growth factor binding protein-3 : structure and function

    Author : Maria Ahlsén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Insulin-like growth factor (IGF) -I and -II share structural homology with insulin. Their receptors and intracellular signaling are similar. Consequently, the biological actions of IGFs and insulin are overlapping. Insulin is secreted on demand depending on e. READ MORE

  6. 9. Signaling to the immature brain - Choroid plexus, insulin-like growth factor 1 and extracellular vesicles

    Author : Niklas Ortenlöf; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IGF-1; Choroid plexus; Immature brain; Extracellular vesicle; CSF; Preterm infants;

    Abstract : Extremely preterm infants (i.e., born below 28 gestational weeks), are at high risk of developing brain morbidities including intraventricular hemorrhage (IVH) and neurodevelopmental impairment. Despite over 50 years of research, there is currently no effective therapy available for preventing IVH. READ MORE

  7. 10. On testosterone during alcohol withdrawal in men : effects on mood and insulin-like growth factor 1

    Author : Jaan Ruusa; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Ethyl alcohol; withdrawal; testosterone; insulin-like growth factor 1; mood;

    Abstract : The decrease of testosterone levels after alcohol ingestion is seen in both non-alcoholic and alcohol dependent patients. Mood effects during hangover and alcohol detoxification are common symptoms. In ageing men a connection has been observed between lowered testosterone levels and depressive symptoms as well as cognitive impairment. READ MORE