Search for dissertations about: "insulin-like growth factor-I"

Showing result 1 - 5 of 79 swedish dissertations containing the words insulin-like growth factor-I.

  2. 1. Formulation studies on human insulin-like growth factor I

    Author : Jonas Fransson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Abstract : .... READ MORE

  4. 2. Insulin-like Growth Factor-I (IGF-I) and Interleukin-6 (IL-6) regulate body fat

    Author : Kristina Wallenius; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; insulin-like growth factor I IGF-I ; interleukin-6 IL-6 ; growth hormone GH ; GH releasing factor GHRF ; GH secretagogue GHS ; receptor; leptin; insulin; glucose; intracerebroventricular ICV ; dual-energy X-ray absorptiometry DXA ; indirect calorimetry.;

    Abstract : The aim of this thesis was to investigate the role of insulin-like growth factor-I (IGF-I) and interleukin-6 (IL-6) in the regulation of metabolism and body fat mass. Circulating IGF-I is mainly liver derived, while a large part of circulating IL-6 is produced by adipose tissue. READ MORE

  5. 3. Experimental studies on the effects of insulin-like growth factor I and glucocorticoids on bone metabolism

    Author : Kenneth B. Jonsson; Uppsala universitet; []
    Keywords : Medical sciences; Bone; bone resorption; glucocorticoids; insulin-like growth factor I; osteoblasts; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Osteoporosis is a major cause of disability among patients that are dependent on glucocorticoids in the treatment of inflammatory disease. The pathogenesis behind this side effect is complex, involving dysregulation of hormonal systems and direct effects on bone cells. READ MORE

  6. 4. Insulin-like growth factor-I from a perspective of bone regeneration

    Author : Per Prisell; Karolinska Institutet; Karolinska Institutet; []
    Keywords : insulin-like growth factor-I; fracture healing; endochondral bone formation; slow release; indomethacin; corticosteroids; hyaluronan; von Kossa;

    Abstract : The insulin-like growth factor I (IGF-I) is produced by osteoblasts and many other cell types. IGF-I is abundant in bone matrix and mediates some of the effects of growth hormone (GH). The present investigations have focused on IGF-I actions during bone regeneration. READ MORE

  7. 5. Insulin-like growth factor-I deficiency, insulin sensitivity, and glucose metabolism

    Author : Klas Ekström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In children and adolescents, growth hormone (GH) and insulin-like growth factor-I (IGF-I) act in concert to stimulate linear growth; however, the effects on glucose metabolism are in opposition. GH increases insulin resistance by lipolysis. READ MORE