Search for dissertations about: "integrin"

Showing result 1 - 5 of 176 swedish dissertations containing the word integrin.

  1. 1. Structural and Functional Aspects of β1 Integrin Signalling

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Stina Nilsson; Staffan Johansson; Teet Velling; Maria Fällman; [2006]
    Keywords : Cell and molecular biology; Integrin; Integrin subunit β1; Integrin activation; Threonine; Phosphorylation; Integrin signalling; FAK; PI3K; MAPK; Cell- och molekylärbiologi;

    Abstract : Integrins are transmembrane glycoproteins primarily mediating interactions of cells with the extracellular matrix. Each receptor is a complex of one α- and one β-subunit with affinity for a diverse set of ligands. READ MORE

  2. 2. Mechanisms of Integrin Signal Transduction

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Anne Stefansson; Uppsala universitet.; [2007]
    Keywords : Cell biology; Integrin; Integrin signalling; PI3K; Akt PKB; Integrin transmembrane domain; cell spreading; Cellbiologi;

    Abstract : Integrins are a protein family of cell surface receptors, expressed in all cell types in the human body, except the red blood cells. Besides their importance in mediating physical connections with the surrounding environment, the integrin family members are also vital signalling mediators. READ MORE

  3. 3. Functional studies of integrin subunit 1 and its cytoplasmic domain

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Krister Wennerberg; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; integrin; integrin subunit β1; integrin signaling; extracellular matrix; fibronectin polymerisation; focal adhesions; focal adhesion kinase; metastasis; Biokemi; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi; Medical Biochemistry; medicinsk biokemi;

    Abstract : Integrin subunit β1 can form functional heterodimeric receptors together with at least 11different a subunits. These integrins are the main cellular receptors for extracellular matrixproteins such as collagens, fibronectin, laminins, and others, and they are necessary fornormal embryonal development. READ MORE

  4. 4. Functional analysis of the alpha10beta1 integrin

    University dissertation from Therese Bengtsson (Cartela AB) or from library

    Author : Therese Bengtsson; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cytogenetics; Genetik; cytogenetik; limb; gene targeting; chondrocyte; integrin; cartilage;

    Abstract : The aim of this thesis was to study the function of the integrin a10b1. Integrins mediate signals between cells and their environment and regulate several cellular processes such as cell migration, proliferation and differentiation. READ MORE

  5. 5. Integrin Signaling in Cell Adhesion and Mechanotransduction Regulation of PI3K, AKT, and ROS

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Kathrin Stephanie Zeller; Staffan Johansson; Kristofer Rubin; John Couchman; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; integrin; ROS; PI3K; AKT; mechanosignaling; actin polymerization; spreading;

    Abstract : Integrins are a family of conserved cell surface receptors found throughout the animal kingdom. They comprise 24 dimers in mammals, and regulate a number of processes including cell survival, differentiation, and migration. READ MORE