Search for dissertations about: "interferon-gamma"

Showing result 16 - 20 of 74 swedish dissertations containing the word interferon-gamma.

  2. 16. Leukocyte activation in newborns in relation to prenatal stress

    Author : Elham Yektaei-Karin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The aim of this project is to describe the pattern of innate immunity responses at birth with focus on the recruitment of leukocytes such as eosinophils and neutrophils and their content of cathelicidin antimicrobial peptide LL-37 associated to different degrees of fetal stress and delivery modes. We know that delivery is associated to fetal stress including release of cortisol and cathecolamines. READ MORE

  4. 17. Interaction between the nervous and immune systems in allergic contact dermatitis : a clinical and experimental study with emphasis on the role of VIP and serotonin

    Author : Lena Bondesson Lundeberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : patch test; nickel sulphate; serotonin antagonists; VIP receptors; immunohistochemistry; ELISA; RIA; HPLC;

    Abstract : The interaction between the nervous and immune systems was investigated in allergic contact dermatitis (ACD) with emphasis on the role of vasoactive intestinal peptide (VIP) and serotonin (S-HT). Dual dose-dependent effects of VIP on the migration of mononuclear and polymorphonuclear leukocytes were found. READ MORE

  5. 18. Pain-related sodium channels in sensory neurons : gene expression during development and after injury

    Author : Jonas Thun; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Pain that goes on over years as a result of nerve damage is an affliction which disables millions of people worldwide. Chronic injury-induced pain can become severely debilitating and extremely difficult to treat. READ MORE

  6. 19. Combined chemotherapy and immunotherapy against experimental malignant brain tumors

    Author : Sara Fritzell; Neurokirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cisplatin; Glioma; GM-CSF; IFN-gamma; IL-7; Immunotherapy; Intratumoral chemotherapy; Temozolomide;

    Abstract : Glioblastoma multiforme (GBM) is the most common and aggressive primary malignant brain tumor in adults. Despite standard treatment including surgery, radiotherapy and temozolomide (TMZ)-based chemotherapy, the prognosis for GBM patients is dismal, and there is a need for novel treatments. READ MORE

  7. 20. On the cytotoxic and proinflammatory properties of eosinophils

    Author : Terese Dajotoy; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi; bacteriology; Microbiology; CXC chemokines; inflammation; eosinophils; cytotoxic mechanisms;

    Abstract : Eosinophils are multi-functional leukocytes involved in the pathophysiology of inflammatory diseases such as asthma and inflammatory bowel disease. Participation in some neoplastic diseases and in the host defense against helminths has also been postulated. They are considered both good and bad, protecting or harming the host. READ MORE