Search for dissertations about: "interleukin-6"

Showing result 26 - 30 of 157 swedish dissertations containing the word interleukin-6.

  2. 26. Effects of prenatal IL-6 exposure and hyperinsulinemia on neuroendocrine regulation

    Author : Anne-Maj Samuelsson; Göteborgs universitet; []
    Keywords : interleukin-6; intrauterine exposure; HPA-axis; RAS; hippocampus; spatial learning; hypertension; insulin signaling; cardiac hypertrophy;

    Abstract : Prenatal exposure to infection is associated with several neuroendocrine disorders. We therefore wanted to elucidate if cytokines, generated in response to maternal infection, play a key mechanistic role in this associations. READ MORE

  4. 27. Effects of growth hormone on bone tissue in transgenic mice

    Author : Jonas Sandstedt; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone; bone; ovariectomy; orchidectomy; growth; Interleukin-6; titanium; transgenic mice;

    Abstract : Growth hormone (GH) affect bone-tissue in both humans and rodents. Also sex steroids are important for growth and the maintenance of normal bone physiology. The specific aims of this study were to investigate how high levels of GH affects bone tissue in mice and to determine whether these effects are dependent on an intact gonadal function. READ MORE

  5. 28. Oxygen delivery and mitochondrial dysfunction as assessed by microdialysis during interventions in experimental sepsis

    Author : Magnus von Seth; Lipscey Miklós; Jan Sjölin; Mats Eriksson; Jukka Takala; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; animal models; microdialysis; endotoxin; Escherichia coli; tigecycline; doxycycline; albumins; capillary leak syndrome; lactic acid; oxygen delivery; multiple organ failure; mitochondria; tumor necrosis factor alpha; interleukin-6; cyanides; ouabain; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Abstract : Early administration of broad-spectrum antibiotics is the first goal in sepsis treatment. Besides from bacteriostatic/bactericidal effects, some antibiotics may also modify the host´s response to infection. The novel antibiotic tigecycline may exert such properties; however, this property has not been evaluated in large-animal trials. READ MORE

  6. 29. Body composition, arteriosclerosis and exercise training in patients with chronic kidney disease

    Author : Yunan Zhou; Njurmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic kidney disease CKD ; exercise training; muscle mass; Sarcopenia; arteriosclerosis; Abdominal aortic calcification AAC ; myostatin; Lipids; lipoproteins; Fibroblast growth factor 23; fetuin-A; Interleukin 6;

    Abstract : .... READ MORE

  7. 30. On the genetic variation of interleukin-6 in health and coronary heart disease

    Author : Marie Björnstedt Bennermo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Atherosclerosis; coronary heart disease; factor VIIa; genetics; inflammation; interleukin-6; pathogen burden; polymorphism;

    Abstract : There is increasing evidence that inflammation plays an important role in the development of atherosclerosis and coronary heart disease (CHD). Prospective studies on healthy individuals and on patients with unstable angina pectoris or non-Q-wave myocardial infarction have shown that individuals with high interleukin-6 (IL-6) concentrations have an increased risk of myocardial infarction and death due to cardiovascular disease. READ MORE