Search for dissertations about: "interleukin-6"

Showing result 6 - 10 of 157 swedish dissertations containing the word interleukin-6.

  2. 6. Cytokines and lipids in pregnancy – effects on developmental programming and placental nutrient transfer

    Author : Susanne Lager; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose tissue; amino acids; cytokines; developmental programming; free fatty acids; insulin resistance; interleukin-6; lipoprotein lipase; nutrient transport; placenta; toll-like receptor 4;

    Abstract : Metabolic disturbances, in particular those associated with nutritional challenges, that take place during development, both in utero and early postnatal life, have long-lasting health consequences on an individual. The most pronounced evidence of these challenges is a deviation in birth weight. READ MORE

  4. 7. Inflammatory cytokines and NFκB in Alzheimer’s disease

    Author : Linda Fisher; Kerstin Iverfeldt; Illana Gozes; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; β-amyloid; interleukin-1; interleukin-6; cell-penetrating peptide; PNA; Neurochemistry; Neurokemi;

    Abstract : Alzheimer’s disease is the most common form of dementia. It is a neurodegenerative disorder characterized by extracellular senile plaques and intracellular neurofibrillary tangles. The main constituent of the senile plaques is the neurotoxic β-amyloid peptide. READ MORE

  5. 8. Pathophysiological role and clinical relevance of cytokines in hypertensive heart failure. A combined clinical and experimental study

    Author : Espen Haugen; Göteborgs universitet; []
    Keywords : Heart failure; cytokines; elderly; hypertension; cardiac remodelling; interleukin 6; etanercept; adiponectin;

    Abstract : Although mortality due to heart failure has decreased significantly in the last decade since the introduction of ACE-inhibitors and ?-adrenergic receptor blockers in the management of heart failure, chronic heart failure is still one of the most important causes of morbidity and mortality and has a very high frequency for readmission to hospitalization because of the aggravation of heart failure. This accounts for a significantly higher health-care expenditure that is twice as much the cost for cancer. READ MORE

  6. 9. The impact of the progranulin-sortilin axis on breast cancer stem cell activity and patient outcome

    Author : Karoline Berger; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; biomarker; cancer stem cells; microenvironment; progranulin; sortilin; interleukin-6; targeted therapy; prognostic;

    Abstract : Breast cancer is the most common cancer in women worldwide. Still today, despite current breast cancer therapies, many patients experience treatment resistance and relapse, which are believed to be due to failure in targeting treatment-resistant cancer stem cells. READ MORE

  7. 10. A role of CD44 in atherosclerosis? Studies in mice and humans

    Author : Sara Sjöberg; Göteborgs universitet; []
    Keywords : CD44; atherosclerosis; interleukin-6; T cell; mast cell;

    Abstract : Atherosclerosis is an inflammatory disease that can lead to clinical complications such as myocardial infarction and stroke. Expressed in both vascular and inflammatory cells, adhesion molecule CD44 can be cleaved from the cell surface, and soluble CD44 can be detected in blood. READ MORE