Search for dissertations about: "intermittent preventive therapy"

Found 3 swedish dissertations containing the words intermittent preventive therapy.

  1. 1. Modelling and Simulation to Improve Antimalarial Therapy

    University dissertation from Upppsala : Acta Universitatis Upsaliensis

    Author : Jesmin Permala Lohy Das; Mats Karlsson; Martin Bergstrand; Joel Tarning; Mads Krielgaard; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacometrics; pharmacokinetics; pharmacodynamics; malaria; artemisinin; weekly dosing; resistant; pregnant populations; intermittent preventive therapy; parasite clearance; day 3 positivity; nomogram; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Abstract : The introduction of artemisinin-based combination therapy (ACT) substantially reduced malaria-related mortality and morbidity during the past decade. Despite the widespread use of ACT, there is still a considerable knowledge gap with regards to safety, efficacy and pharmacokinetic properties of these drugs, particularly in vulnerable populations like children and pregnant women. READ MORE

  2. 2. Screening for atrial fibrillation in high-risk individuals : a stroke preventive effort

    University dissertation from Stockholm : Karolinska Institutet, Dept of Clinical Sciences, Danderyd Hospital

    Author : Emma Svennberg; Karolinska Institutet.; Karolinska Institutet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : INTRODUCTION A condition can be suitable for population screening if the disease is an important health problem, can be detected by an appropriate test and has a silent/latent stage during which treatment could be initiated in order to prevent consequences of the disease. Atrial fibrillation (AF) increases the risk of ischemic stroke 5-fold, a risk that can be reduced by at least 64% by the use of stroke-preventive, oral anticoagulant (OAC) therapy, and there are several non-invasive methods that can be used to diagnose AF. READ MORE

  3. 3. Role of PfATP6 and pfMRP1 in Plasmodium falciparum resistance to antimalarial drugs

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Sabina Dahlström; Karolinska Institutet.; Karolinska Institutet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Half of the world s population live at risk for malaria and nearly one million people die from the disease every year. The malaria burden is greatest in children and pregnant women in sub-Saharan Africa. READ MORE