Search for dissertations about: "internalisation"

Showing result 1 - 5 of 29 swedish dissertations containing the word internalisation.

  2. 1. Cellular Studies of HER-family Specific Affibody Molecules

    Author : Lovisa Göstring; Lars Gedda; Jörgen Carlsson; Fredrik Frejd; Håkan Hedman; Uppsala universitet; []
    Keywords : EGFR; HER2; HER3; Affibody; internalisation; tumour targeting; MEDICINE; MEDICIN;

    Abstract : The human epidermal growth-factor like receptor (HER) family of receptor tyrosine kinases are important targets for cancer therapy. The family consists of four members - EGFR, HER2, HER3 and HER4 - that normally transfer stimulatory signals from extracellular growth factors to the intracellular signalling network. READ MORE

  4. 2. Cellular Uptake of Cystatin C. Subcellular localisation and intracellular effects of a secreted cysteine protease inhibitor

    Author : Hanna Wallin; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cathepsin; cell line; co-localisation; cystatin C; internalisation; legumain;

    Abstract : Cystatin C is a cysteine protease inhibitor, aimed for secretion, as it is produced with a signal peptide. Its target enzymes are thought to be the lysosomal cysteine cathepsins and legumain. READ MORE

  5. 3. Antibiotic resistance and pathogenesis of Streptococci with focus on Group A Streptococci

    Author : Feiruz Alamiri; Malmö Experimentell infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibiotika resistens; Bröstmjölk; Luftvägsinfektioner; Biofilm bildning; Internalisering; Persistens; HAMLET; Streptokocker; kolonisering; Streptococcus pneumoniae; biofilm formation; Internalisation; Persistence; Antibiotic resistance; Streptococcus pyogenes; Streptococcus agalactiae; HAMLET; Breast milk; Proteome; Virulence factors; Colonization;

    Abstract : Multi-drug resistant (MDR) infections remain the leading cause of death worldwide. MDR infections caused by Streptococcus pneumoniae (Spn), Streptococcus pyogenes (GAS) and Streptococcus agalactiae (GBS) are considered global threats to human health due to increased spread of antibiotic resistance and limited treatment options. READ MORE

  6. 4. Issues of making hydropower environmentally sustainable

    Author : Inger Poveda Björklund; KTH; []
    Keywords : Hydropower planning; Environmental impact assessment; Integration of EIA finding; Legal framework for EIA; Internalisation;

    Abstract : .... READ MORE

  7. 5. Staphylococcal cell wall associated proteins : characteristics and host interactions

    Author : Anna Bjertsjö Rennermalm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Staphylococcus; aureus; epidermidis; cell wall; surface; protein; fibronectinbinding protein; fibrinogen binding protein; internalisation; immunisation; endocarditis; opsonisation;

    Abstract : Staphylococcus aureus and Staphylococcus epidermidis are members of the same family and share several features. S. aureus causes many diseases ranging from mild skin infections to deep tissue infections and septic shock. S. READ MORE