Search for dissertations about: "internalization"
Showing result 1 - 5 of 169 swedish dissertations containing the word internalization.
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1. Structures, toxicity and internalization of cell-penetrating peptides
Abstract : Cellular internalization is a highly regulated process controlled by proteins in the plasma membrane. Large and hydrophilic compounds, in particular, face difficulties conquering the plasma membrane barrier in order to gain access to intracellular environment. This puts serious constrains on the drug industry since many drugs are hydrophilic. READ MORE
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2. Analysis of PDGF receptor internalization and signaling using proximity ligation assays
Abstract : Cell signaling is mediated by signaling proteins that relay the signal in an intricate network of interactions before the signal is translated into a biological response. Short linear motifs (SLiMs) in intrinsically disordered regions of proteins serve as docking sites for protein interaction in all aspects of cell regulation including signal transduction. READ MORE
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3. The Internalization of External Effects in Swedish Transport Policy - A Comparison Between Road and Rail Traffic
Abstract : Transport is a key factor for economic growth. It has enabled both the economic scale of production and an increase in competition. No one can question this role of transportation. There is, however, a back-side to the coin: the environmental challenge. READ MORE
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4. REGULATED UPTAKE OF BIOPOLYMERS Role of cell surface proteoglycans Implications for drug and gene delivery
Abstract : Cells continuously export, import, and recycle molecules over the plasma membrane. Internalization, i.e. cellular import of extracellular material, is a fundamental process, which provides cells with nutrients and enables the immune cells of higher organisms to remove debris, sample their surroundings for antigens and to fight microbes. READ MORE
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5. Novel Methods for Analysis of Heterogeneous Protein-Cell Interactions : Resolving How the Epidermal Growth Factor Binds to Its Receptor
Abstract : Cells are complex biological units with advanced signalling systems, a dynamic capacity to adapt to its environment, and the ability to divide and grow. In fact, they are of such high level of complexity that it has deemed extremely difficult or even impossible to completely understand cells as complete units. READ MORE