Search for dissertations about: "internalization"
Showing result 11 - 15 of 169 swedish dissertations containing the word internalization.
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11. Naturally derived cell-penetrating peptides and applications in gene regulation : A study on internalization mechanisms and endosomal escape
Abstract : Cell-penetrating peptides are a class of peptides which have achieved a lot of recognition due to their vector abilities. Since their discovery over a decade ago, there has been an uncertainty concerning the mechanism by which they are internalized into the cells. READ MORE
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12. Regulation of internalization and replication of intracellular bacterial pathogens
Abstract : The capacity of intracellular bacteria to cause disease depends on their ability to invade and replicate within eukaryotic host cells. These characteristics also allow preferential invasion and replication by facultative anaerobic bacteria in solid tumours, which can be exploited to design delivery vectors for cancer therapy. READ MORE
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13. Delivery of gene-regulating agents : internalization mechanisms and novel vectors
Abstract : The sequencing of the human genome was expected to generate a veritable explosion of therapeutics for regulation of gene function, either through modulation of gene expression or through the replacement of defect genes. However, nucleic acid-based pharmacological agents suffer from issues of low bioavailability and unfavorable pharmacokinetics, wherefore these prospects have not yet been realized. READ MORE
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14. Cell responses in infected and cystic fibrosis respiratory epithelium
Abstract : Respiratory Epithelium. Örebro Studies in Medicine 99. Cystic fibrosis (CF) is caused by a mutation in a cAMP-activated chloride (Cl-) channel (CFTR). Mortality and morbidity in CF is mainly due to the deregulated responses of the airway epithelial cells. READ MORE
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15. Exploring the internalization of University-lndustry Collaboration and firm innovation: an analysis of influential roles, problem, and implementation paths
Abstract : The phenomenon studied here is how cooperatively developed knowledge, resulting from knowledge-related interaction in a university–industry collaboration (UIC), is internally utilized by a firm. The purpose of this research is to explore how knowledge developed in a UIC is utilized by the collaborating firm in the development of innovations. READ MORE