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Showing result 1 - 5 of 81 swedish dissertations matching the above criteria.

2. 1. Artery Wall Imaging and Effects of Postmenopausal Estrogen Therapy

   Author : Kenny A. Rodriguez-Macias Wallberg; Tord Naessén; Lars-Åke Mattsson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; artery wall thickness; tunica media; tunica intima; arterial stiffness; carotid; aorta; cardiovascular disease; atherosclerosis; menopause; estrogen; hormone therapy; ultrasound; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

   Abstract : Postmenopausal estrogen therapy, initiated early in the menopause, seems to protect against development of atherosclerosis and cardiovascular diseases. This thesis concerns studies of artery wall thickness and arterial stiffness estimated by noninvasive ultrasound techniques in long-term estrogen treated postmenopausal women who initiated therapy at the time of the menopause. READ MORE

4. 2. Studies on arterial endothelial function and intima-media thickness using ultrasound technique

   Author : Morteza Rohani; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Ultrasound; atherosclerosis; flow mediated dilatation; endothelial function; carotid arteries; thoracic aorta; brachial artery; coronary artery disease; nicotine; snuff; prednisolone; rheumatoid arthritis;

   Abstract : Background: The development of ultrasonographic arterial imaging, high-resolution B-mode ultrasonography, has created a technical basis for a new diagnostic approach to atherosclerotic disease by offering the possibility of accurate and reproducible quantification of the structural and functional changes in the arterial wall. Flow-mediated dilation (FMD) of the brachial artery and carotid intima-media thickness (IMT) have been shown to be good surrogate markers of atherosclerosis. READ MORE

5. 3. Cardiovascular regulation and vascular structure in prehypertension and coronary heart disease

   Author : Anna Myredal; Göteborgs universitet; []
   Keywords : prehypertension; coronary heart disease; repolarization; baroreflex; intima thickness; CABG; non-dippers;

   Abstract : The aim of this thesis was to characterize vascular structure and different aspects of cardiovascular regulation in otherwise healthy subjects with slightly elevated blood pressure and compare to healthy subjects with normotension and also investigate patients with established primary or secondary hypertension and coronary heart disease. Altered cardiac repolarization and arterial baroreflex function has been associated with adverse prognosis and increased risk for ventricular arrhythmias in patients with cardiovascular diseases. READ MORE

6. 4. Cardiovascular Disease and Immune Mechanisms in Systemic Lupus Erythematosus

   Author : Dag Leonard; Lars Rönnblom; Gunnel Nordmark; Maija-Leena Eloranta; Søren Jacobsen; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic Lupus Erythematosus; Cardiovascular Disease; Intima-Media Thickness; STAT4; IRF8; Interferon-α; Plasmacytoid dendritic cell; GM-CSF; IL-3; Medicin; Medicine; Genetics; Genetik; Immunologi; Immunology;

   Abstract : Systemic lupus erythematosus (SLE) is an autoimmune, inflammatory disease characterized by autoantibody production and an activated type I interferon system. Cardiovascular disease (CVD) is as a major cause of morbidity and mortality. The aim of this thesis was to identify genetic risk factors for CVD in SLE. READ MORE

7. 5. Cardiovascular structure and function in obesity. The impact of body composition, sleep apnea and sustained weight loss

   Author : Dimitris Kardassis; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; weight loss; cardiac function; cardiac structure; inflammation; intima-media thickness; obstructive sleep apnoea;

   Abstract : Background: Obesity is associated with disturbances in cardiovascular structure and function varying along with the degree of fatness, but the mechanisms underlying this co-variation are unclear. Short-term weight loss appears to have favourable effects on the cardiovascular system, but whether such improvements are maintained in the long run is unknown. READ MORE