Search for dissertations about: "intracellular replication"
Showing result 1 - 5 of 67 swedish dissertations containing the words intracellular replication.
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1. The Francisella pathogenicity island : its role in type VI secretion and intracellular infection
Abstract : Intracellular bacteria have developed various mechanisms to enter and persist in host cells and, at the same time, to evade the host immune response. One such pathogen is Francisella tularensis, the etiological agent of tularemia. READ MORE
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2. Regulation of internalization and replication of intracellular bacterial pathogens
Abstract : The capacity of intracellular bacteria to cause disease depends on their ability to invade and replicate within eukaryotic host cells. These characteristics also allow preferential invasion and replication by facultative anaerobic bacteria in solid tumours, which can be exploited to design delivery vectors for cancer therapy. READ MORE
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3. The cell cycle of the hyperthermophilic archaeal genus Sulfolobus
Abstract : The third domain of life, Archaea is one of the three main evolutionary lineages together with the Bacteria and the Eukarya domains. The archaea are, despite their prokaryotic cell organisation, more closely related to eukaryotes than to bacteria in terms of the informational pathways (DNA replication, transcription and translation). READ MORE
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4. Mechanisms of the intracellular survival of Francisella tularensis
Abstract : Francisella tularensis is a gram-negative, highly virulent, intracellular bacterium which causes the zoonotic disease tularemia. The subspecies tularensis and holarctica are clinically important, and the former is the more virulent. The intracellular lifestyle of F. READ MORE
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5. Intracellular pathways involved in formation and degradation of prions
Abstract : Prions cause invariably fatal neurodegenerative diseases, in which a misfolded host-encoded protein appears to be the main, if not the only, component of the infectious agent. During disease, a normal cellular protein, PrPC, is converted to a disease-related isoform, PrPSc, by a post-translational process that might require auxiliary cellular cofactors. READ MORE