Search for dissertations about: "intracellular signaling pathway"

Showing result 1 - 5 of 151 swedish dissertations containing the words intracellular signaling pathway.

  2. 1. Adrenergic signaling in insulin-sensitive tissues

    Author : Daniel L. Yamamoto; Tore Bengtsson; Barbara Cannon; Michael Cawthorne; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Metabolism; Adrenergic; Glucose; Signaling; Skeletal muscle; Animal physiology; Zoofysiologi; zoofysiologi; Zoological physiology;

    Abstract : Glucose metabolism in insulin-sensitive tissues such as skeletal muscle and adipose tissue is tightly regulated by external stimuli. Metabolic changes in these tissues have direct effects on whole body metabolism. Such metabolic changes can be induced or influenced by adrenergic stimulation. READ MORE

  4. 2. Regulation of intracellular signaling events that modulate insulin action

    Author : Silvia Gogg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insulin; insulin resistance; EGF; Gab 1; insulin receptor substrate; PI3-kinase; ; Thiazolidinediones; PPARã; insulin signaling; glucose transport; adipose tissue; â-cell.;

    Abstract : Insulin regulates several mechanisms of fundamental importance to the body involving glucose, fat andprotein metabolism. Insulin resistance in skeletal muscle, liver and adipose tissue promotes an increaseddemand for insulin secretion. READ MORE

  5. 3. Regulation of Hyaluronan Synthesis and Signaling via CD44 in Cancer

    Author : Merima Mehić; Paraskevi Heldin; Carl-Henrik Heldin; Liliana Schaefer; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hyaluronan; CD44; TGFβ; PDGF-BB; cancer; signaling; hyaluronan synthase; epithelial-mesenchymal transition; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Medical Science; Medicinsk vetenskap;

    Abstract : Hyaluronan is a ubiquitous glycosaminoglycan which is an important constituent of the extracellular matrix (ECM). In addition to organizing the extracellular matrix and regulating tissue homeostasis, hyaluronan, by binding to its main cell surface receptor CD44, is involved in intracellular signaling pathways regulating major cellular processes during development, wound healing, inflammation and cancer. READ MORE

  6. 4. Plasticity of the dopamine1 receptor and its signaling pathway

    Author : Maria Sol Kruse; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Dopamine; D1R; trafficking; signaling pathway; NMDA;

    Abstract : Dopamine 1 receptor (D1R) belongs to the G protein coupled receptor superfamily with seven transmembrane domains. Previous studies from our laboratory showed that D1R availability in the plasma membrane of renal epithelial cells is dynamically regulated by the dopaminergic tonus. Here, we *examined the availability of D1R in the brain. READ MORE

  7. 5. Novel Regulators of the TGF-β Signaling Pathway

    Author : Marcin Kowanetz; Aristidis Moustakas; Carl-Henrik Heldin; Caroline Hill; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; TGF-β; Smad; Id; EMT; cell cycle; SNF1LK; ubiquitin; degradation; signal transduction; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : The transforming growth factor-β (TGF-β) superfamily consists of related multifunctional cytokines, which include TGF-βs, activins, and bone morphogenetic proteins (BMPs) and coordinate several biological responses in diverse cell types. The biological activity of TGF-β members is executed by transmembrane serine/threonine kinase receptors and intracellular Smad proteins. READ MORE