Search for dissertations about: "intracellular"
Showing result 1 - 5 of 1531 swedish dissertations containing the word intracellular.
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1. Intracellular amyloid : a study of choroid plexus epithelial cells and adrenal cortical cells
Abstract : .... READ MORE
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2. β-adrenergic stimulation of VEGF gene expression : intracellular signalling pathways
Abstract : In the present study, the intracellular signalling pathway mediating ß-adrenergic stimulation of the expression of the vascular endothelial growth factor (VEGF) gene was investigated.VEGF is an activator of angiogenesis, the formation of new blood vessels, and is considered to be a major regulator of both physiologically and pathologically related angiogenesis, as well as being essential for development of the vascular system. READ MORE
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3. Intracellular unbound drug concentrations : Methodology and application for understanding cellular drug exposure
Abstract : Most known drug targets and metabolizing enzymes are located inside cells. Interactions with these proteins are determined by intracellular unbound drug concentrations. Assessing intracellular drug exposure is technically challenging, but essential for predicting pharmacokinetic, pharmacological, and toxicological profiles of new drugs. READ MORE
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4. Intracellular processing of pre-a-inhibitor
Abstract : Pre-α-inhibitor (PαI) is a plasma protein consisting of a 25 and a 75 kDa polypeptide: bikunin and heavy chain 3 (H3), respectively. Both these polypeptides are made by hepatocytes and while passing through the Golgi complex, bikunin, which carries a chondroitin sulfate chain, becomes covalently linked to the C-terminal amino acid residue of H3 via its polysaccharide. READ MORE
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5. Intracellular Flows and Fluctuations
Abstract : Mathematical models are now gaining in importance for descriptions of biological processes. In this thesis, such models have been used to identify and analyze principles that govern bacterial protein synthesis under amino acid limitation. READ MORE