Search for dissertations about: "intracellular"

Showing result 6 - 10 of 1531 swedish dissertations containing the word intracellular.

2. 6. Studies on intracellular phosphoproteins : the cyclic 3',5'-amp-dependent phosphorylation of pyruvate kinase (type L)

   Author : Olle Ljungström; Uppsala universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : .... READ MORE

4. 7. Characterization of parameters influencing intracellular bioavailability and prediction of intracellular drug exposure

   Author : Andrea Treyer; Per Artursson; Gert Fricker; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intracellular drug bioavailability; unbound drug concentration; drug disposition; ADME; drug transport; drug metabolism membrane partitioning; phospholipid; drug-drug interaction; antisense oligonucleotide; cell-penetrating peptide; Farmaceutisk vetenskap; Pharmaceutical Science;

   Abstract : This thesis work investigates factors influencing intracellular drug disposition. An experimental method for measurement of intracellular bioavailability (Fic), was used throughout. Fic is defined as the ratio between the unbound drug concentration inside the cell and the compound concentration in the cell exterior. READ MORE

5. 8. The Francisella pathogenicity island : its role in type VI secretion and intracellular infection

   Author : Lena Meyer; Anders Sjöstedt; Siobhan C. Cowley; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella; FPI; Type VI Secretion; Igl; DotU; VgrG; Pdp; microinjection; phagosomal escape; intracellular replication; Clinical Bacteriology; klinisk bakteriologi;

   Abstract : Intracellular bacteria have developed various mechanisms to enter and persist in host cells and, at the same time, to evade the host immune response. One such pathogen is Francisella tularensis, the etiological agent of tularemia. READ MORE

6. 9. Mucosal immunity in the respiratory tract : The role of IgA in protection against intracellular pathogens

   Author : Ariane Rodríguez; Carmen Fernández; Lennart Hammarström; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucosal immunity; respiratory tract; IgA; intracellular pathogens; Immunology; Immunologi;

   Abstract : The lungs and upper airways are mucosal surfaces that are common site for infection with an enormous variety of inhaled pathogens. Therefore, induction of immune responses in the respiratory tract is crucial for protection against respiratory diseases. One of the pathogens infecting the host via the respiratory tract is Mycobacterium Tuberculosis. READ MORE

7. 10. Platelets : intracellular signalling and cellular interaction

   Author : Magnus Grenegård; Hans Gyllenhammar; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : Activation of platelets is essential to prevent excessive blood loss at the site of vascular injury. These highly reactive cell fragments are also involved in several pathological conditions, in particular arterial thrombosis, which, in the coronary vessels, can lead to reduced blood flow, vessel occlusion and myocardial infarction. READ MORE