Search for dissertations about: "intragastric pH"

Found 3 swedish dissertations containing the words intragastric pH.

  1. 1. The importance of the CYP2C19 polymorphism for disposition and effects of omeprazole treatment

    Author : Mohamed Sagar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Omeprazole; CYP2C19; H. pylori; gastrin; intragastric pH; vitamin B12;

    Abstract : CYP2C19, catalyzes the metabolism of omeprazole and several other drugs. About 3% of Caucasians are poor metabolizers (PM) of these drugs. The goal of this thesis was to evaluate the importance of CYP2C19 polymorphism for disposition and clinical effects of omeprazole treatment in healthy subjects and in patients with acid related disorders. READ MORE

  2. 2. Gastric acid secretion and gut peptides : mechanisms involved in inflammatory response

    Author : Tobias Rudholm Feldreich; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The regulation of gastric acid secretion is complex and involves endocrine, paracrine, and neurocrine mechanisms. Among these, the interconnecting cross-talk between different gut peptides is an important part in the control of acid secretion. READ MORE

  3. 3. Nitrite ion : its role in vasoregulation and host defenses

    Author : Håkan Björne; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Nitrate; nitrite; nitric oxide; gastro protection; ventilator-associated pneumonia; bactericidal; vasodilation;

    Abstract : Nitrite and nitrate are distributed throughout the human body, with especially high levels being present in saliva. Until recently, these anions were considered merely to be inert end-products of the oxidation of endogenous nitric oxide (NO). READ MORE