Search for dissertations about: "intrahepatic cholestasis of pregnancy"

Found 3 swedish dissertations containing the words intrahepatic cholestasis of pregnancy.

2. 1. Intrahepatic cholestasis of pregnancy

   Author : Anna Glantz; Göteborgs universitet; []
   Keywords : Intrahepatic cholestasis of pregnancy ICP ; pruritus; fetal risk; ursodeoxycholic acid; dexamethasone; ABCB4-gene; haplotypes; sulphated progesterone metabolites;

   Abstract : Intrahepatic cholestasis of pregnancy (ICP) is a condition that has been reported to be associated with an increased fetal risk. A prospective study of ICP was conducted in the Västra Götaland region of Sweden between February 1, 1999 and January 31, 2002. READ MORE

4. 2. Clinical and pathophysiological aspects of intrahepatic cholestasis of pregnancy

   Author : Elisabeth A Wikström Shemer; Karolinska Institutet; Karolinska Institutet; []
   Keywords : intrahepatic cholestasis of pregnancy;

   Abstract : Objective: The pathogenesis of intrahepatic cholestasis of pregnancy (ICP) involves impaired bile acid and estrogen/progesterone metabolism and excretion based on genetic and environmental factors. In this thesis we evaluated different pathophysiological and clinical aspects of ICP, i.e. READ MORE

5. 3. Steroids and bile acids in intrahepatic cholestasis of pregnancy : effects of treatment with ursodeoxycholic acid

   Author : Ling-Jie Meng; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : A method permitting simultaneous analysis of individual steroid hormone metabolites and bile acids in different forms of conjugation in serum and urine was established. Total bile acids and neutral steroids were extracted from human serum or urine with octadecylsilane-bonded silica, separated into different groups of conjugates by anion-exchange chromatography and analyzed by fast atom bombardment mass spectrometry. READ MORE